Source: INFERRED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808 221
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808 216
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769 209
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885 205
BAZ1B Q9UIG0 bromodomain adjacent to zinc finger domain 1B 1.00 0.530 0.731 202
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 187
GTF2I P78347 general transcription factor IIi 1.00 0.500 0.808 187
TRPS1 Q9UHF7 transcriptional repressor GATA binding 1 1.00 0.537 0.769 174
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923 170
JMJD1C Q15652 jumonji domain containing 1C 1.00 0.517 0.769 169
TCF4 P15884 transcription factor 4 Transcription factor 1.00 0.464 0.846 165
SETBP1 Q9Y6X0 SET binding protein 1 1.00 0.503 0.808 160
RREB1 Q92766 ras responsive element binding protein 1 1.00 0.500 0.808 159
NSD1 Q96L73 nuclear receptor binding SET domain protein 1 Epigenetic regulator 1.00 0.505 0.769 158
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 153
RAI1 Q7Z5J4 retinoic acid induced 1 Transcription factor 1.00 0.545 0.731 153
KAT6B Q8WYB5 lysine acetyltransferase 6B Enzyme 1.00 0.525 0.731 152
RERE Q9P2R6 arginine-glutamic acid dipeptide repeats 1.00 0.526 0.846 148
SETD5 Q9C0A6 SET domain containing 5 1.00 0.560 0.731 145
MAP2K1 Q02750 mitogen-activated protein kinase kinase 1 Kinase 0.90 0.439 0.846 144
SCN2A Q99250 sodium voltage-gated channel alpha subunit 2 Ion channel 1.00 0.518 0.731 141
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923 140
EHMT1 Q9H9B1 euchromatic histone lysine methyltransferase 1 Epigenetic regulator 1.00 0.460 0.808 140
ROR2 Q01974 receptor tyrosine kinase like orphan receptor 2 Kinase 1.2E-04 0.498 0.731 139