Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 101
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 94
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 62
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 60
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 59
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885 44
CCL5 P13501 C-C motif chemokine ligand 5 Signaling 1.8E-03 0.403 0.885 40
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846 34
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 32
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 32
CX3CL1 P78423 C-X3-C motif chemokine ligand 1 Signaling 0.61 0.478 0.808 27
CX3CR1 P49238 C-X3-C motif chemokine receptor 1 G-protein coupled receptor 6.1E-02 0.457 0.885 27
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923 27
CD40LG P29965 CD40 ligand Signaling 0.72 0.414 0.846 26
MIF P14174 macrophage migration inhibitory factor 1.2E-02 0.412 0.885 26
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923 16
CLU P10909 clusterin 7.8E-05 0.426 0.885 14
DUSP1 P28562 dual specificity phosphatase 1 1.0E-02 0.491 0.808 13
SELP P16109 selectin P 5.0E-32 0.460 0.769 12
MMP14 P50281 matrix metallopeptidase 14 Enzyme 1.00 0.447 0.769 11
SLIT2 O94813 slit guidance ligand 2 1.00 0.511 0.769 11
MAPK8 P45983 mitogen-activated protein kinase 8 Kinase 1.00 0.397 0.885 10
PTK2B Q14289 protein tyrosine kinase 2 beta Kinase 0.94 0.448 0.808 10