Source: GWASCAT

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808 100 16
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 94 101
GCKR Q14397 glucokinase regulator 8.5E-19 0.604 0.615 79 13
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692 74 8
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885 61 54
CYP21A2 P08686 cytochrome P450 family 21 subfamily A member 2 2.6E-04 0.525 0.769 52 70
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846 48 44
LPP Q93052 LIM domain containing preferred translocation partner in lipoma Enzyme modulator 7.2E-03 0.543 0.769 46 45
TSBP1-AS1 TSBP1 and BTNL2 antisense RNA 1 0.638 0.692 44 49
TMEM258 P61165 transmembrane protein 258 1.9E-03 0.644 0.654 40 13
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 38 13
HLA-DQA1 P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 2.4E-02 0.416 0.846 37 36
MYRF Q9Y2G1 myelin regulatory factor 1.00 0.584 0.731 37 13
ZPR1 O75312 ZPR1 zinc finger 8.9E-09 0.674 0.462 36 16
JMJD1C Q15652 jumonji domain containing 1C 1.00 0.517 0.769 35 48
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 33 42
HLA-DQB1 P01920 major histocompatibility complex, class II, DQ beta 1 Immune response 8.9E-03 0.407 0.885 33 30
ZBTB38 Q8NAP3 zinc finger and BTB domain containing 38 Transcription factor 1.00 0.663 0.615 32 33
IL6R P08887 interleukin 6 receptor Signaling 3.2E-05 0.471 0.846 32 19
CPS1 P31327 carbamoyl-phosphate synthase 1 Enzyme 1.1E-09 0.590 0.615 32 5
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731 30 48
ZFPM2 Q8WW38 zinc finger protein, FOG family member 2 Transcription factor 1.00 0.565 0.731 30 27
MARK4 Q96L34 microtubule affinity regulating kinase 4 Kinase 1.00 0.641 0.615 28 44
NOTCH4 Q99466 notch receptor 4 2.1E-23 0.534 0.731 27 20