Source: GENOMICS_ENGLAND

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769 14
CDK8 P49336 cyclin dependent kinase 8 Kinase 0.41 0.597 0.654 11
ZIC3 O60481 Zic family member 3 Transcription factor 0.92 0.587 0.423 10
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846 9
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769 8
SOX4 Q06945 SRY-box transcription factor 4 Transcription factor 0.93 0.489 0.808 7
WDPCP O95876 WD repeat containing planar cell polarity effector 1.1E-10 0.576 0.769 7
EDNRB P24530 endothelin receptor type B G-protein coupled receptor 9.2E-03 0.470 0.846 6
LCA5 Q86VQ0 lebercilin LCA5 4.1E-05 0.674 0.269 5
MNX1 P50219 motor neuron and pancreas homeobox 1 Transcription factor 0.79 0.555 0.615 5
SGCD Q92629 sarcoglycan delta Cellular structure 2.1E-03 0.641 0.615 5
STIM1 Q13586 stromal interaction molecule 1 0.78 0.501 0.808 5
CASK O14936 calcium/calmodulin dependent serine protein kinase Kinase 1.00 0.538 0.808 4
RFX6 Q8HWS3 regulatory factor X6 Transcription factor 4.1E-04 0.686 0.385 4
INTU Q9ULD6 inturned planar cell polarity protein 7.7E-10 0.555 0.769 3
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885 3
MYCN P04198 MYCN proto-oncogene, bHLH transcription factor Transcription factor 0.89 0.454 0.808 3
SIL1 Q9H173 SIL1 nucleotide exchange factor 1.2E-02 0.584 0.731 3
TTC7A Q9ULT0 tetratricopeptide repeat domain 7A 1.5E-31 0.641 0.577 3
CCNQ Q8N1B3 cyclin Q Enzyme modulator 0.90 0.663 0.462 2
FOXF1 Q12946 forkhead box F1 0.96 0.540 0.692 2
TNNI3K Q59H18 TNNI3 interacting kinase 3.1E-48 0.691 0.346 2
AMOTL1 Q8IY63 angiomotin like 1 1.8E-03 0.736 0.423 1
CDH18 Q13634 cadherin 18 0.21 0.769 0.269 1