Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846 17
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769 14
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731 13
FANCA O15360 FA complementation group A 1.6E-68 0.505 0.731 13
FANCC Q00597 FA complementation group C 2.8E-13 0.507 0.808 13
FANCG O15287 FA complementation group G 2.5E-14 0.556 0.769 13
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769 12
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846 11
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885 11
FANCE Q9HB96 FA complementation group E 1.5E-06 0.553 0.808 11
FANCF Q9NPI8 FA complementation group F 0.46 0.535 0.731 11
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692 11
FANCI Q9NVI1 FA complementation group I 8.9E-37 0.543 0.731 10
FANCL Q9NW38 FA complementation group L Enzyme 5.9E-23 0.551 0.731 10
FANCM Q8IYD8 FA complementation group M Enzyme 2.4E-15 0.543 0.731 9
GATA1 P15976 GATA binding protein 1 0.95 0.483 0.808 9
SLX4 Q8IY92 SLX4 structure-specific endonuclease subunit 1.6E-22 0.565 0.731 9
RPS19 P39019 ribosomal protein S19 Nucleic acid binding 0.92 0.480 0.846 8
SALL1 Q9NSC2 spalt like transcription factor 1 Transcription factor 1.00 0.539 0.808 7
RPL11 P62913 ribosomal protein L11 Nucleic acid binding 0.96 0.650 0.577 6
RPL26 P61254 ribosomal protein L26 Nucleic acid binding 0.92 0.695 0.423 5
RPL5 P46777 ribosomal protein L5 Nucleic acid binding 1.00 0.617 0.615 5
SALL4 Q9UJQ4 spalt like transcription factor 4 Transcription factor 1.00 0.489 0.769 5
RPS10 P46783 ribosomal protein S10 Nucleic acid binding 0.97 0.729 0.462 4