Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
COL4A1 P02462 collagen type IV alpha 1 chain 1.00 0.484 0.731 21
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808 16
ACVRL1 P37023 activin A receptor like type 1 Kinase 9.7E-04 0.493 0.769 14
COL4A5 P29400 collagen type IV alpha 5 chain 1.00 0.553 0.654 14
FLNA P21333 filamin A 1.00 0.419 0.846 14
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808 13
COL11A1 P12107 collagen type XI alpha 1 chain 1.00 0.495 0.846 12
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846 12
COL1A2 P08123 collagen type I alpha 2 chain 1.00 0.486 0.846 10
COL5A2 P05997 collagen type V alpha 2 chain 1.00 0.568 0.731 10
COL9A2 Q14055 collagen type IX alpha 2 chain 1.0E-08 0.572 0.769 10
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885 10
ENG P17813 endoglin 1.00 0.446 0.846 9
COL5A1 P20908 collagen type V alpha 1 chain 1.00 0.536 0.769 8
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769 8
COL18A1 P39060 collagen type XVIII alpha 1 chain 1.7E-10 0.449 0.808 7
COL3A1 P02461 collagen type III alpha 1 chain 1.00 0.477 0.808 7
COL9A1 P20849 collagen type IX alpha 1 chain 3.1E-19 0.566 0.731 7
ELN P15502 elastin 2.1E-14 0.415 0.885 7
FOXE3 Q13461 forkhead box E3 Transcription factor 0.18 0.568 0.654 6
JAG1 P78504 jagged canonical Notch ligand 1 1.00 0.429 0.808 6
SMAD6 O43541 SMAD family member 6 Transcription factor 3.6E-20 0.579 0.731 6
TGFB3 P10600 transforming growth factor beta 3 Signaling 0.99 0.498 0.808 6
ACTA2 P62736 actin alpha 2, smooth muscle Cellular structure 0.93 0.508 0.846 5