Source: UNIPROT

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846 17 14
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885 16 32
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808 13 34
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 13 33
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846 13 28
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808 12 18
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769 11 17
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885 10 57
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 10 34
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 10 32
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 10 29
CDH1 P12830 cadherin 1 0.15 0.401 0.808 10 8
SCN5A Q14524 sodium voltage-gated channel alpha subunit 5 Ion channel 0.91 0.513 0.654 9 344
LMNA P02545 lamin A/C 1.00 0.384 0.885 9 102
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 9 44
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808 9 9
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846 8 78
LRP5 O75197 LDL receptor related protein 5 0.51 0.485 0.846 8 54
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808 8 36
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885 8 24
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 8 18
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885 7 45
MPZ P25189 myelin protein zero 0.27 0.503 0.846 7 42
COL7A1 Q02388 collagen type VII alpha 1 chain Receptor 2.4E-40 0.545 0.808 7 39