Source: RGD

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.300 None 0.956 6 0 1994 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.300 None 0.935 3 0 1996 2020
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.300 None 0.929 1 0 1999 2020
Entrez Id: 3586
Gene Symbol: IL10
IL10
interleukin 10 0.281 0.923 5.9E-03
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.300 None 1.000 1 0 1995 2019
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
interferon gamma 0.288 0.962 0.47
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.250 None 1.000 1 0 1997 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2 apoptosis regulator 0.291 0.885 0.56
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.210 None 1.000 1 0 2009 2013
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.240 None 1.000 1 0 2011 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
insulin like growth factor 1 0.318 0.885 0.27
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.220 None 1.000 2 0 2002 2020
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
C-C motif chemokine ligand 2 0.321 0.962 0.61
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.220 None 1.000 1 0 2002 2019
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
toll like receptor 4 0.321 0.962 4.6E-09
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.300 None 1.000 1 0 2006 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE
angiotensin I converting enzyme 0.328 0.923 1.0E-37
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.210 None 1.000 1 0 1987 2018
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
interleukin 1 alpha 0.333 0.962 1.6E-04
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.250 None 0.833 1 0 1999 2020
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
ATP binding cassette subfamily B member 1 0.344 0.885 1.3E-05
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.200 None 1.000 1 0 2016 2016
Entrez Id: 836
Gene Symbol: CASP3
CASP3
caspase 3 0.351 0.923 0.10
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.200 None 1.000 1 0 2013 2013
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
peroxisome proliferator activated receptor gamma 0.358 0.885 2.9E-02
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.210 None 1.000 1 0 2011 2017
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
serpin family E member 1 0.359 0.885 4.4E-02
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.240 None 1.000 2 0 2002 2019
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
toll like receptor 2 0.361 0.923 1.0E-06
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.210 None 1.000 1 0 2006 2011
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
nitric oxide synthase 2 0.364 0.923 4.0E-15
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.540 None 1.000 2 0 2003 2019
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
intercellular adhesion molecule 1 0.364 0.962 3.5E-02
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.220 None 1.000 1 0 2007 2017
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
high mobility group box 1 0.368 0.923 0.82
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.300 None 1.000 1 0 2004 2019
Entrez Id: 355
Gene Symbol: FAS
FAS
Fas cell surface death receptor 0.372 0.923 0.81
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.200 None 1.000 1 0 2010 2010
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
interleukin 1 receptor antagonist 0.373 0.923 3.1E-02
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.210 None 1.000 1 0 1992 2013
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
adiponectin, C1Q and collagen domain containing 0.376 0.885 4.6E-09
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.200 None 1.000 1 0 2013 2013
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
nitric oxide synthase 3 0.378 0.885 6.7E-07
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.210 None 1.000 1 0 1999 2020
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
mitogen-activated protein kinase 14 0.379 0.923 0.37
CUI: C0376618
Disease: Endotoxemia
Endotoxemia
phenotype 0.210 None 1.000 2 0 2011 2013