Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4879
Gene Symbol: NPPB
NPPB
natriuretic peptide B 0.513 0.808 9.9E-06
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.530 None 1.000 1 0 2005 2011
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
endothelin 1 0.380 0.846 0.46
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.530 None 1.000 1 0 1994 2010
Entrez Id: 94
Gene Symbol: ACVRL1
ACVRL1
activin A receptor like type 1 0.493 0.769 9.7E-04
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.510 None 1.000 1 0 2003 2016
Entrez Id: 959
Gene Symbol: CD40LG
CD40LG
CD40 ligand 0.414 0.846 0.72
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 None 1.000 1 0 2004 2015
Entrez Id: 3741
Gene Symbol: KCNA5
KCNA5
potassium voltage-gated channel subfamily A member 5 0.606 0.500 1.1E-03
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 None 1.000 1 0 2010 2017
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
nuclear factor of activated T cells 2 0.525 0.731 1.00
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 None 1.000 1 0 2007 2017
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
nitric oxide synthase 2 0.364 0.923 4.0E-15
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.220 None 1.000 1 0 2006 2006
Entrez Id: 10911
Gene Symbol: UTS2
UTS2
urotensin 2 0.564 0.808 3.2E-02
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.210 None 1.000 1 0 2004 2005
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
cellular communication network factor 2 0.399 0.846 5.0E-04
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.210 None 1.000 1 0 2005 2009
Entrez Id: 284
Gene Symbol: ANGPT1
ANGPT1
angiopoietin 1 0.446 0.808 0.95
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.210 None 1.000 1 0 2006 2008
Entrez Id: 183
Gene Symbol: AGT
AGT
angiotensinogen 0.367 0.923 5.0E-08
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.210 None 1.000 1 0 2004 2011
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.210 None 1.000 1 0 2002 2008
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
serpin family E member 1 0.359 0.885 4.4E-02
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2016 2016
Entrez Id: 5139
Gene Symbol: PDE3A
PDE3A
phosphodiesterase 3A 0.670 0.577 1.9E-04
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2002 2002
Entrez Id: 5154
Gene Symbol: PDGFA
PDGFA
platelet derived growth factor subunit A 0.533 0.731 0.81
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 1993 1993
Entrez Id: 5175
Gene Symbol: PECAM1
PECAM1
platelet and endothelial cell adhesion molecule 1 0.426 0.846
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2012 2012
Entrez Id: 498
Gene Symbol: ATP5F1A
ATP5F1A
ATP synthase F1 subunit alpha 0.604 0.731 1.00
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2011 2011
Entrez Id: 488
Gene Symbol: ATP2A2
ATP2A2
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 0.529 0.808 1.00
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2016 2016
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
natriuretic peptide A 0.505 0.769 5.5E-04
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 1990 1990
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2011 2011
Entrez Id: 3596
Gene Symbol: IL13
IL13
interleukin 13 0.386 0.846 1.4E-02
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2009 2009
Entrez Id: 3038
Gene Symbol: HAS3
HAS3
hyaluronan synthase 3 0.644 0.692 0.88
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2010 2010
Entrez Id: 4091
Gene Symbol: SMAD6
SMAD6
SMAD family member 6 0.579 0.731 3.6E-20
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2007 2007
Entrez Id: 4092
Gene Symbol: SMAD7
SMAD7
SMAD family member 7 0.470 0.769 0.55
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2007 2007
Entrez Id: 4093
Gene Symbol: SMAD9
SMAD9
SMAD family member 9 0.666 0.308 6.4E-05
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2007 2007