Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
natriuretic peptide A 0.505 0.769 5.5E-04
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 1990 1990
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1
serpin family A member 1 0.410 0.923 6.8E-08
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 1991 1991
Entrez Id: 5154
Gene Symbol: PDGFA
PDGFA
platelet derived growth factor subunit A 0.533 0.731 0.81
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 1993 1993
Entrez Id: 241
Gene Symbol: ALOX5AP
ALOX5AP
arachidonate 5-lipoxygenase activating protein 0.612 0.731 7.1E-02
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 1996 1996
Entrez Id: 11318
Gene Symbol: GPR182
GPR182
G protein-coupled receptor 182 0.691 0.462 1.4E-04
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2002 2002
Entrez Id: 5139
Gene Symbol: PDE3A
PDE3A
phosphodiesterase 3A 0.670 0.577 1.9E-04
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2002 2002
Entrez Id: 10800
Gene Symbol: CYSLTR1
CYSLTR1
cysteinyl leukotriene receptor 1 0.593 0.769 1.2E-02
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2003 2003
Entrez Id: 6865
Gene Symbol: TACR2
TACR2
tachykinin receptor 2 0.700 0.500 8.8E-05
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2003 2003
Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase 0.529 0.692 1.00
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2003 2003
Entrez Id: 6869
Gene Symbol: TACR1
TACR1
tachykinin receptor 1 0.502 0.885 3.8E-04
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2003 2003
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
tachykinin precursor 1 0.424 0.923 0.75
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2003 2003
Entrez Id: 5740
Gene Symbol: PTGIS
PTGIS
prostaglandin I2 synthase 0.617 0.654 1.2E-09
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 2 0 1999 2004
Entrez Id: 2034
Gene Symbol: EPAS1
EPAS1
endothelial PAS domain protein 1 0.454 0.731 0.60
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2005 2005
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
bradykinin receptor B2 0.585 0.808 0.12
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2005 2005
Entrez Id: 10911
Gene Symbol: UTS2
UTS2
urotensin 2 0.564 0.808 3.2E-02
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.210 None 1.000 1 0 2004 2005
Entrez Id: 211
Gene Symbol: ALAS1
ALAS1
5'-aminolevulinate synthase 1 0.705 0.462 0.11
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2005 2005
Entrez Id: 64344
Gene Symbol: HIF3A
HIF3A
hypoxia inducible factor 3 subunit alpha 0.682 0.538 1.5E-03
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2005 2005
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
baculoviral IAP repeat containing 5 0.495 0.731 5.6E-02
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2005 2005
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
nitric oxide synthase 2 0.364 0.923 4.0E-15
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.220 None 1.000 1 0 2006 2006
Entrez Id: 387
Gene Symbol: RHOA
RHOA
ras homolog family member A 0.502 0.808 0.60
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 2 0 2006 2007
Entrez Id: 4093
Gene Symbol: SMAD9
SMAD9
SMAD family member 9 0.666 0.308 6.4E-05
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2007 2007
Entrez Id: 1524
Gene Symbol: CX3CR1
CX3CR1
C-X3-C motif chemokine receptor 1 0.457 0.885 6.1E-02
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2007 2007
Entrez Id: 4092
Gene Symbol: SMAD7
SMAD7
SMAD family member 7 0.470 0.769 0.55
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2007 2007
Entrez Id: 4091
Gene Symbol: SMAD6
SMAD6
SMAD family member 6 0.579 0.731 3.6E-20
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2007 2007
Entrez Id: 5970
Gene Symbol: RELA
RELA
RELA proto-oncogene, NF-kB subunit 0.406 0.885 1.00
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 1 0 2007 2007