| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
phenotype | 0.600 | None | 1.000 | 3 | 0 | 1995 | 2020 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
phenotype | 0.580 | None | 1.000 | 2 | 0 | 1995 | 2019 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
phenotype | 0.600 | None | 1.000 | 3 | 0 | 1995 | 2019 | ||||||||
|
interleukin 10 | 0.281 | 0.923 | 5.9E-03 |
|
phenotype | 0.510 | None | 1.000 | 2 | 0 | 1995 | 2017 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
phenotype | 0.600 | None | 1.000 | 1 | 0 | 2004 | 2020 | ||||||||
|
signal transducer and activator of transcription 3 | 0.320 | 0.923 | 1.00 |
|
phenotype | 0.210 | None | 1.000 | 1 | 0 | 2013 | 2018 | ||||||||
|
C-C motif chemokine ligand 2 | 0.321 | 0.962 | 0.61 |
|
phenotype | 0.570 | None | 1.000 | 3 | 0 | 2007 | 2019 | ||||||||
|
toll like receptor 4 | 0.321 | 0.962 | 4.6E-09 |
|
phenotype | 0.270 | None | 1.000 | 1 | 0 | 2010 | 2019 | ||||||||
|
interleukin 17A | 0.324 | 0.923 | 4.3E-02 |
|
phenotype | 0.220 | None | 1.000 | 2 | 0 | 2012 | 2017 | ||||||||
|
hypoxia inducible factor 1 subunit alpha | 0.327 | 0.923 | 0.98 |
|
phenotype | 0.200 | None | 1.000 | 1 | 0 | 2008 | 2008 | ||||||||
|
interleukin 2 | 0.336 | 0.885 | 0.48 |
|
phenotype | 0.200 | None | 1.000 | 3 | 0 | 2003 | 2012 | ||||||||
|
mechanistic target of rapamycin kinase | 0.343 | 0.885 | 1.00 |
|
phenotype | 0.220 | None | 1.000 | 1 | 0 | 2014 | 2019 | ||||||||
|
brain derived neurotrophic factor | 0.345 | 0.923 | 0.66 |
|
phenotype | 0.290 | None | 1.000 | 4 | 0 | 1998 | 2019 | ||||||||
|
catalase | 0.359 | 0.962 | 1.6E-10 |
|
phenotype | 0.200 | None | 1.000 | 2 | 0 | 2013 | 2014 | ||||||||
|
toll like receptor 2 | 0.361 | 0.923 | 1.0E-06 |
|
phenotype | 0.210 | None | 1.000 | 1 | 0 | 2013 | 2018 | ||||||||
|
C-X-C motif chemokine receptor 4 | 0.362 | 0.923 | 1.8E-02 |
|
phenotype | 0.230 | None | 1.000 | 2 | 0 | 2017 | 2019 | ||||||||
|
interleukin 18 | 0.365 | 0.923 | 3.1E-02 |
|
phenotype | 0.240 | None | 1.000 | 1 | 0 | 2008 | 2019 | ||||||||
|
high mobility group box 1 | 0.368 | 0.923 | 0.82 |
|
phenotype | 0.520 | None | 1.000 | 2 | 0 | 2014 | 2019 | ||||||||
|
interleukin 1 receptor antagonist | 0.373 | 0.923 | 3.1E-02 |
|
phenotype | 0.520 | None | 1.000 | 2 | 0 | 1996 | 2019 | ||||||||
|
C-X-C motif chemokine ligand 12 | 0.379 | 0.846 | 0.12 |
|
phenotype | 0.210 | None | 1.000 | 1 | 0 | 2017 | 2019 | ||||||||
|
Janus kinase 2 | 0.385 | 0.885 | 0.65 |
|
phenotype | 0.200 | None | 1.000 | 1 | 0 | 2008 | 2008 | ||||||||
|
nerve growth factor | 0.391 | 0.885 | 0.82 |
|
phenotype | 0.600 | None | 0.957 | 3 | 0 | 1998 | 2020 | ||||||||
|
gap junction protein alpha 1 | 0.393 | 0.885 | 0.16 |
|
phenotype | 0.220 | None | 1.000 | 2 | 0 | 2013 | 2019 | ||||||||
|
C-C motif chemokine receptor 5 (gene/pseudogene) | 0.398 | 0.885 | 4.3E-10 |
|
phenotype | 0.210 | None | 1.000 | 2 | 0 | 2007 | 2017 | ||||||||
|
estrogen receptor 2 | 0.400 | 0.923 | 4.5E-08 |
|
phenotype | 0.200 | None | 1.000 | 1 | 0 | 2006 | 2006 |