| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Bardet-Biedl syndrome 4 | 0.647 | 0.615 | 1.5E-16 |
|
group | 0.010 | None | < 0.001 | 1 | 0 | 2002 | 2002 | ||||||||
|
epoxide hydrolase 2 | 0.568 | 0.654 | 1.8E-21 |
|
group | 0.100 | None | 0.700 | 1 | 0 | 2006 | 2018 | ||||||||
|
cystathionine beta-synthase | 0.465 | 0.885 | 3.1E-05 |
|
group | 0.390 | None | 0.778 | 1 | 0 | 1996 | 2015 | ||||||||
|
clock circadian regulator | 0.463 | 0.885 | 1.00 |
|
group | 0.050 | None | 0.800 | 1 | 0 | 2008 | 2018 | ||||||||
|
prostaglandin-endoperoxide synthase 1 | 0.460 | 0.885 | 6.2E-07 |
|
group | 0.050 | None | 0.800 | 1 | 0 | 2000 | 2016 | ||||||||
|
potassium voltage-gated channel subfamily Q member 1 | 0.485 | 0.769 | 4.5E-08 |
|
group | 0.050 | None | 0.800 | 1 | 0 | 2005 | 2020 | ||||||||
|
chromogranin A | 0.490 | 0.808 | 3.0E-02 |
|
group | 0.060 | None | 0.833 | 1 | 0 | 2008 | 2018 | ||||||||
|
homeostatic iron regulator | 0.436 | 0.846 | 2.6E-08 |
|
group | 0.060 | None | 0.833 | 1 | 0 | 2001 | 2008 | ||||||||
|
estrogen receptor 1 | 0.324 | 0.962 | 1.00 |
|
group | 0.100 | None | 0.862 | 1 | 0 | 2003 | 2019 | ||||||||
|
apolipoprotein A1 | 0.429 | 0.885 | 5.5E-04 |
|
group | 0.100 | None | 0.881 | 3 | 0 | 1995 | 2019 | ||||||||
|
matrix metallopeptidase 2 | 0.333 | 0.923 | 0.84 |
|
group | 0.100 | None | 0.882 | 2 | 0 | 2007 | 2020 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
group | 0.400 | None | 0.889 | 1 | 0 | 2004 | 2019 | ||||||||
|
estrogen receptor 2 | 0.400 | 0.923 | 4.5E-08 |
|
group | 0.100 | None | 0.900 | 1 | 0 | 2006 | 2017 | ||||||||
|
toll like receptor 4 | 0.321 | 0.962 | 4.6E-09 |
|
group | 0.100 | None | 0.909 | 1 | 0 | 2005 | 2019 | ||||||||
|
cholesteryl ester transfer protein | 0.512 | 0.731 | 1.2E-23 |
|
group | 0.400 | None | 0.914 | 6 | 0 | 2002 | 2020 | ||||||||
|
intercellular adhesion molecule 1 | 0.364 | 0.962 | 3.5E-02 |
|
group | 0.400 | None | 0.917 | 1 | 0 | 2002 | 2019 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
group | 0.400 | None | 0.923 | 8 | 0 | 1996 | 2020 | ||||||||
|
growth hormone 1 | 0.373 | 0.923 | 3.0E-02 |
|
group | 0.400 | None | 0.923 | 2 | 0 | 2003 | 2019 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
group | 0.100 | None | 0.923 | 2 | 0 | 2002 | 2019 | ||||||||
|
interleukin 10 | 0.281 | 0.923 | 5.9E-03 |
|
group | 0.100 | None | 0.923 | 2 | 0 | 2000 | 2019 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
group | 0.100 | None | 0.929 | 8 | 0 | 2002 | 2020 | ||||||||
|
coagulation factor III, tissue factor | 0.415 | 0.846 | 1.9E-02 |
|
group | 0.100 | None | 0.933 | 1 | 0 | 2006 | 2018 | ||||||||
|
matrix metallopeptidase 9 | 0.305 | 0.923 | 1.9E-17 |
|
group | 0.100 | None | 0.941 | 1 | 0 | 2003 | 2019 | ||||||||
|
angiotensin II receptor type 1 | 0.423 | 0.846 | 5.3E-04 |
|
group | 0.100 | None | 0.943 | 2 | 0 | 1998 | 2020 | ||||||||
|
resistin | 0.454 | 0.808 | 3.7E-02 |
|
group | 0.100 | None | 0.947 | 1 | 0 | 2002 | 2019 |