Source: ANIMAL_MODELS

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2632
Gene Symbol: GBE1
GBE1
1,4-alpha-glucan branching enzyme 1 0.612 0.654 1.1E-12
CUI: C0017923
Disease: Glycogen Storage Disease Type IV
Glycogen Storage Disease Type IV
disease 1.000 None 1.000 3 0 1996 2017
Entrez Id: 10555
Gene Symbol: AGPAT2
AGPAT2
1-acylglycerol-3-phosphate O-acyltransferase 2 0.585 0.654 1.2E-07
CUI: C0023787
Disease: Lipodystrophy
Lipodystrophy
disease 0.700 strong 1.000 2 0 2002 2016
Entrez Id: 10555
Gene Symbol: AGPAT2
AGPAT2
1-acylglycerol-3-phosphate O-acyltransferase 2 0.585 0.654 1.2E-07
Lipodystrophy, not elsewhere classified
disease 0.200 None 1.000 2 0 2009 2016
Entrez Id: 10555
Gene Symbol: AGPAT2
AGPAT2
1-acylglycerol-3-phosphate O-acyltransferase 2 0.585 0.654 1.2E-07
Congenital Generalized Lipodystrophy Type 1
disease 0.930 None 0.857 2 0 2002 2019
Entrez Id: 3248
Gene Symbol: HPGD
HPGD
15-hydroxyprostaglandin dehydrogenase 0.516 0.731 1.4E-05
CUI: C0007097
Disease: Carcinoma
Carcinoma
group 0.250 None 1.000 1 0 2005 2011
Entrez Id: 3248
Gene Symbol: HPGD
HPGD
15-hydroxyprostaglandin dehydrogenase 0.516 0.731 1.4E-05
CUI: C0015967
Disease: Fever
Fever
phenotype 0.210 None 1.000 1 0 2003 2004
Entrez Id: 3248
Gene Symbol: HPGD
HPGD
15-hydroxyprostaglandin dehydrogenase 0.516 0.731 1.4E-05
CUI: C0030920
Disease: Peptic Ulcer
Peptic Ulcer
disease 0.300 None 1.000 1 0 2013 2013
Entrez Id: 3248
Gene Symbol: HPGD
HPGD
15-hydroxyprostaglandin dehydrogenase 0.516 0.731 1.4E-05
CUI: C0553707
Disease: Malignant epithelioma
Malignant epithelioma
disease 0.200 None 1.000 1 0 2008 2008
Entrez Id: 3248
Gene Symbol: HPGD
HPGD
15-hydroxyprostaglandin dehydrogenase 0.516 0.731 1.4E-05
CUI: C1368683
Disease: Epithelioma
Epithelioma
disease 0.200 None 1.000 1 0 2008 2008
Entrez Id: 1267
Gene Symbol: CNP
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase 0.604 0.692 0.98
Experimental Autoimmune Encephalomyelitis
disease 0.200 None 1.000 3 0 1995 2011
Entrez Id: 1267
Gene Symbol: CNP
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase 0.604 0.692 0.98
CUI: C0007282
Disease: Carotid Stenosis
Carotid Stenosis
disease 0.200 None 1.000 1 0 2007 2007
Entrez Id: 1267
Gene Symbol: CNP
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase 0.604 0.692 0.98
CUI: C0752308
Disease: Hypoxia-Ischemia, Brain
Hypoxia-Ischemia, Brain
disease 0.200 None 1.000 1 0 2009 2009
Entrez Id: 4938
Gene Symbol: OAS1
OAS1
2'-5'-oligoadenylate synthetase 1 0.626 0.654 3.4E-05
CUI: C0019193
Disease: Hepatitis, Toxic
Hepatitis, Toxic
disease 0.200 None 1.000 1 0 2007 2007
Entrez Id: 4938
Gene Symbol: OAS1
OAS1
2'-5'-oligoadenylate synthetase 1 0.626 0.654 3.4E-05
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.200 None 1.000 1 0 2007 2007
Entrez Id: 4938
Gene Symbol: OAS1
OAS1
2'-5'-oligoadenylate synthetase 1 0.626 0.654 3.4E-05
CUI: C1262760
Disease: Hepatitis, Drug-Induced
Hepatitis, Drug-Induced
disease 0.200 None 1.000 1 0 2007 2007
Entrez Id: 4938
Gene Symbol: OAS1
OAS1
2'-5'-oligoadenylate synthetase 1 0.626 0.654 3.4E-05
CUI: C3658290
Disease: Drug-Induced Acute Liver Injury
Drug-Induced Acute Liver Injury
disease 0.200 None 1.000 1 0 2007 2007
Entrez Id: 4938
Gene Symbol: OAS1
OAS1
2'-5'-oligoadenylate synthetase 1 0.626 0.654 3.4E-05
Chemical and Drug Induced Liver Injury
disease 0.200 None 1.000 1 0 2007 2007
Entrez Id: 4938
Gene Symbol: OAS1
OAS1
2'-5'-oligoadenylate synthetase 1 0.626 0.654 3.4E-05
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
disease 0.200 None 1.000 1 0 2007 2007
Entrez Id: 9060
Gene Symbol: PAPSS2
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.682 0.462 2.0E-10
Spondyloepimetaphyseal Dysplasia, Pakistani Type
disease 0.920 None 1.000 3 0 1969 2015
Entrez Id: 9060
Gene Symbol: PAPSS2
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.682 0.462 2.0E-10
Spondylodysplasia And Premature Pubarche
disease 0.200 None 1.000 3 0 1969 1998
Entrez Id: 3155
Gene Symbol: HMGCL
HMGCL
3-hydroxy-3-methylglutaryl-CoA lyase 0.691 0.462 2.6E-06
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
disease 0.200 None 1.000 1 0 1968 1968
Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase 0.529 0.692 1.00
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1
disease 0.200 None 1.000 3 0 2010 2014
Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase 0.529 0.692 1.00
LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1
phenotype 0.200 None 1.000 3 0 2010 2014
Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase 0.529 0.692 1.00
FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 2
phenotype 0.200 None 1.000 3 0 2010 2014
Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase 0.529 0.692 1.00
CUI: C0035126
Disease: Reperfusion Injury
Reperfusion Injury
disease 0.200 None 1.000 2 0 2008 2011