Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.400 None 0.950 1 0 1991 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.600 None 0.984 12 0 1991 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.100 None 1.000 3 0 2001 2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.100 None 1.000 1 0 1995 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2 apoptosis regulator 0.291 0.885 0.56
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.100 None 1.000 1 0 1998 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.100 None 1.000 1 0 2006 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.400 None 1.000 3 0 1991 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.300 0.885 0.39
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.600 None 1.000 8 0 1995 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.300 None 0.972 3 0 1998 2020
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.305 0.923 1.9E-17
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.400 None 0.969 2 0 1994 2020
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
C-X-C motif chemokine ligand 8 0.310 0.962 2.7E-04
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.400 None 1.000 2 0 1997 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.400 None 1.000 2 0 1999 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.320 0.923 1.00
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.100 None 1.000 2 0 2008 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.400 None 1.000 1 0 2001 2019
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
toll like receptor 4 0.321 0.962 4.6E-09
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.100 None 1.000 1 0 2005 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274
CD274 molecule 0.324 0.923 1.9E-02
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.100 None 0.965 1 0 2008 2020
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
hypoxia inducible factor 1 subunit alpha 0.327 0.923 0.98
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.100 None 0.952 1 0 2001 2018
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.328 0.923 6.0E-03
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.100 None 1.000 4 0 1991 2020
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.400 None 0.950 2 0 2002 2019
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
interleukin 1 alpha 0.333 0.962 1.6E-04
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.050 None 1.000 1 0 2003 2018
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
methylenetetrahydrofolate reductase 0.337 0.885 3.2E-10
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.400 None 0.875 2 0 2004 2013
Entrez Id: 4609
Gene Symbol: MYC
MYC
MYC proto-oncogene, bHLH transcription factor 0.344 0.923 1.00
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.400 None 1.000 2 0 1990 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1
cyclin D1 0.344 0.923 0.89
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.100 None 1.000 2 0 1996 2019
Entrez Id: 367
Gene Symbol: AR
AR
androgen receptor 0.351 0.846 0.99
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.100 None 1.000 1 0 2004 2020
Entrez Id: 7421
Gene Symbol: VDR
VDR
vitamin D receptor 0.352 0.885 1.7E-05
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
disease 0.050 None 1.000 1 0 2007 2019