Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.100 None 1.000 4 0 1992 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.500 None 0.900 3 0 1991 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.400 None 0.966 2 0 1989 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.100 None 0.973 4 0 1994 2020
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.100 None 1.000 1 0 1992 2020
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2 apoptosis regulator 0.291 0.885 0.56
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.100 None 0.970 2 0 1996 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.500 None 1.000 1 0 2006 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.100 None 0.952 1 0 1988 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
C-reactive protein 0.299 0.962 3.7E-03
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.100 None 1.000 1 0 2005 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.300 0.885 0.39
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.300 None 1.000 3 0 1991 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.700 None 1.000 4 0 1998 2020
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.305 0.923 1.9E-17
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.100 None 0.944 1 0 2006 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.311 0.962 0.98
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.200 None 1.000 1 0 2007 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.600 None 1.000 2 0 2002 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
insulin like growth factor 1 0.318 0.885 0.27
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.100 None 1.000 2 0 1999 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 0.320 0.885 1.4E-06
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.100 None 1.000 1 0 2006 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.320 0.923 1.00
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.100 None 0.958 1 0 2002 2020
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
C-C motif chemokine ligand 2 0.321 0.962 0.61
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.080 None 1.000 1 0 2001 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.324 0.962 1.00
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.090 None 1.000 2 0 2002 2018
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
hypoxia inducible factor 1 subunit alpha 0.327 0.923 0.98
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.100 None 1.000 7 0 2000 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.100 None 0.875 2 0 2003 2019
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
major histocompatibility complex, class II, DR beta 1 0.333 0.923 1.1E-03
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.040 None 1.000 1 0 1997 2017
Entrez Id: 3558
Gene Symbol: IL2
IL2
interleukin 2 0.336 0.885 0.48
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.100 None 1.000 1 0 1990 2019
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
mechanistic target of rapamycin kinase 0.343 0.885 1.00
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.500 None 0.983 1 0 2004 2020
Entrez Id: 4609
Gene Symbol: MYC
MYC
MYC proto-oncogene, bHLH transcription factor 0.344 0.923 1.00
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
disease 0.300 None 1.000 3 0 1985 2019