| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
group | 0.600 | None | 0.921 | 33 | 0 | 1986 | 2020 | ||||||||
|
angiotensinogen | 0.367 | 0.923 | 5.0E-08 |
|
group | 0.600 | None | 0.971 | 30 | 0 | 1979 | 2020 | ||||||||
|
angiotensin II receptor type 1 | 0.423 | 0.846 | 5.3E-04 |
|
group | 0.600 | None | 0.944 | 19 | 0 | 1993 | 2020 | ||||||||
|
cytochrome P450 family 11 subfamily B member 2 | 0.553 | 0.615 | 7.1E-19 |
|
group | 0.200 | None | 0.969 | 15 | 0 | 1992 | 2019 | ||||||||
|
nitric oxide synthase 3 | 0.378 | 0.885 | 6.7E-07 |
|
group | 0.700 | None | 0.942 | 14 | 0 | 1996 | 2019 | ||||||||
|
adrenoceptor beta 2 | 0.442 | 0.923 | 0.53 |
|
group | 0.300 | None | 0.933 | 12 | 0 | 1989 | 2017 | ||||||||
|
bone morphogenetic protein receptor type 2 | 0.538 | 0.654 | 1.00 |
|
group | 0.200 | None | 1.000 | 10 | 0 | 2002 | 2020 | ||||||||
|
endothelin 1 | 0.380 | 0.846 | 0.46 |
|
group | 0.600 | None | 0.983 | 10 | 0 | 1993 | 2020 | ||||||||
|
adducin 1 | 0.612 | 0.615 | 0.99 |
|
group | 0.600 | None | 0.861 | 9 | 0 | 1995 | 2019 | ||||||||
|
G protein subunit beta 3 | 0.518 | 0.808 | 3.3E-11 |
|
group | 0.400 | None | 0.938 | 9 | 0 | 1998 | 2018 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
group | 0.100 | None | 0.881 | 9 | 0 | 1993 | 2020 | ||||||||
|
renin | 0.370 | 0.923 | 2.4E-07 |
|
group | 0.600 | None | 0.969 | 6 | 0 | 1975 | 2020 | ||||||||
|
lipoprotein lipase | 0.474 | 0.808 | 1.3E-09 |
|
group | 0.400 | None | 0.800 | 6 | 0 | 1998 | 2017 | ||||||||
|
cytochrome b-245 alpha chain | 0.520 | 0.769 | 8.9E-06 |
|
group | 0.600 | None | 0.964 | 6 | 0 | 2002 | 2017 | ||||||||
|
leptin | 0.349 | 0.846 | 0.46 |
|
group | 0.600 | None | 0.972 | 5 | 0 | 1998 | 2020 | ||||||||
|
natriuretic peptide B | 0.513 | 0.808 | 9.9E-06 |
|
group | 0.600 | None | 0.955 | 5 | 0 | 1997 | 2019 | ||||||||
|
natriuretic peptide A | 0.505 | 0.769 | 5.5E-04 |
|
group | 0.600 | None | 0.970 | 5 | 0 | 1989 | 2019 | ||||||||
|
cytochrome P450 family 4 subfamily A member 11 | 0.695 | 0.462 | 1.1E-24 |
|
group | 0.300 | None | 1.000 | 5 | 0 | 2005 | 2018 | ||||||||
|
hydroxysteroid 11-beta dehydrogenase 2 | 0.532 | 0.808 | 0.12 |
|
group | 0.700 | None | 0.964 | 5 | 0 | 1995 | 2019 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
group | 0.600 | None | 1.000 | 5 | 0 | 1996 | 2020 | ||||||||
|
angiotensin I converting enzyme 2 | 0.477 | 0.769 | 1.00 |
|
group | 0.600 | None | 0.982 | 5 | 0 | 2003 | 2019 | ||||||||
|
PPARG coactivator 1 alpha | 0.453 | 0.885 | 1.00 |
|
group | 0.100 | None | 0.947 | 5 | 0 | 2003 | 2019 | ||||||||
|
prostaglandin I2 synthase | 0.617 | 0.654 | 1.2E-09 |
|
group | 0.100 | None | 1.000 | 4 | 0 | 1999 | 2007 | ||||||||
|
solute carrier family 12 member 3 | 0.493 | 0.808 | 3.0E-32 |
|
group | 0.400 | None | 1.000 | 4 | 0 | 2001 | 2019 | ||||||||
|
WNK lysine deficient protein kinase 4 | 0.644 | 0.538 | 6.9E-25 |
|
group | 0.500 | None | 0.909 | 4 | 0 | 2003 | 2020 |