| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.400 | None | 0.986 | 1 | 0 | 1989 | 2019 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.700 | None | 0.947 | 8 | 0 | 1989 | 2020 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
disease | 0.500 | None | 0.971 | 1 | 0 | 1995 | 2020 | ||||||||
|
BCL2 apoptosis regulator | 0.291 | 0.885 | 0.56 |
|
disease | 0.400 | None | 0.978 | 1 | 0 | 1994 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.700 | None | 0.985 | 0 | 0 | 2002 | 2020 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
disease | 0.400 | None | 0.991 | 2 | 0 | 1992 | 2020 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.700 | None | 0.983 | 4 | 0 | 1997 | 2020 | ||||||||
|
C-X-C motif chemokine ligand 8 | 0.310 | 0.962 | 2.7E-04 |
|
disease | 0.400 | None | 1.000 | 1 | 0 | 1996 | 2019 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
disease | 0.600 | limited | 0.984 | 0 | 0 | 2002 | 2020 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
disease | 0.400 | None | 0.979 | 6 | 0 | 1994 | 2020 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
disease | 0.700 | None | 0.976 | 4 | 0 | 2002 | 2020 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.600 | None | 0.963 | 3 | 0 | 1990 | 2020 | ||||||||
|
toll like receptor 4 | 0.321 | 0.962 | 4.6E-09 |
|
disease | 0.400 | None | 1.000 | 2 | 0 | 2006 | 2019 | ||||||||
|
colony stimulating factor 2 | 0.330 | 0.962 | 0.83 |
|
disease | 0.380 | None | 1.000 | 1 | 0 | 2000 | 2018 | ||||||||
|
matrix metallopeptidase 2 | 0.333 | 0.923 | 0.84 |
|
disease | 0.700 | None | 1.000 | 2 | 0 | 1992 | 2019 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
disease | 0.400 | None | 0.932 | 8 | 0 | 1996 | 2019 | ||||||||
|
ATP binding cassette subfamily B member 1 | 0.344 | 0.885 | 1.3E-05 |
|
disease | 0.600 | None | 0.960 | 2 | 0 | 1990 | 2020 | ||||||||
|
MYC proto-oncogene, bHLH transcription factor | 0.344 | 0.923 | 1.00 |
|
disease | 0.400 | None | 1.000 | 1 | 0 | 1990 | 2019 | ||||||||
|
peroxisome proliferator activated receptor gamma | 0.358 | 0.885 | 2.9E-02 |
|
disease | 0.500 | None | 0.938 | 1 | 0 | 2000 | 2019 | ||||||||
|
toll like receptor 2 | 0.361 | 0.923 | 1.0E-06 |
|
disease | 0.400 | None | 1.000 | 2 | 0 | 2006 | 2019 | ||||||||
|
tumor protein p63 | 0.362 | 0.769 | 1.00 |
|
disease | 0.340 | None | 1.000 | 1 | 0 | 2005 | 2019 | ||||||||
|
interferon alpha 1 | 0.371 | 0.923 |
|
disease | 0.330 | None | 1.000 | 1 | 0 | 1999 | 2019 | |||||||||
|
APC regulator of WNT signaling pathway | 0.373 | 0.962 | 1.00 |
|
disease | 0.800 | strong | 0.972 | 7 | 0 | 1990 | 2020 | ||||||||
|
kinase insert domain receptor | 0.378 | 0.885 | 1.00 |
|
disease | 0.600 | None | 0.964 | 1 | 0 | 2002 | 2019 | ||||||||
|
superoxide dismutase 2 | 0.379 | 0.923 | 0.15 |
|
disease | 0.370 | None | 1.000 | 2 | 0 | 2000 | 2017 |