Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
ERCC excision repair 4, endonuclease catalytic subunit | 0.468 | 0.846 | 1.4E-12 |
|
disease | 0.320 | strong | 0.667 | 1 | 0 | 2015 | 2017 | ||||||||
|
interferon regulatory factor 1 | 0.468 | 0.769 | 0.99 |
|
disease | 0.380 | limited | 0.875 | 0 | 0 | 1993 | 2011 | ||||||||
|
RAD51 recombinase | 0.447 | 0.846 | 2.7E-02 |
|
disease | 0.400 | moderate | 0.917 | 1 | 0 | 2004 | 2017 | ||||||||
|
KIT proto-oncogene, receptor tyrosine kinase | 0.366 | 0.808 | 0.98 |
|
disease | 0.800 | moderate | 0.955 | 0 | 0 | 1989 | 2019 | ||||||||
|
DNA methyltransferase 3 alpha | 0.445 | 0.846 | 7.4E-39 |
|
disease | 0.800 | limited | 0.955 | 0 | 0 | 2009 | 2019 | ||||||||
|
FA complementation group B | 0.468 | 0.769 | 1.00 |
|
disease | 0.400 | strong | 0.958 | 1 | 0 | 1982 | 2020 | ||||||||
|
GATA binding protein 2 | 0.496 | 0.654 | 0.98 |
|
disease | 0.800 | None | 0.974 | 3 | 0 | 1994 | 2020 | ||||||||
|
ETS variant transcription factor 6 | 0.477 | 0.731 | 0.97 |
|
disease | 0.800 | strong | 0.981 | 1 | 0 | 1995 | 2019 | ||||||||
|
CCAAT enhancer binding protein alpha | 0.496 | 0.692 | 0.55 |
|
disease | 1.000 | definitive | 0.985 | 3 | 0 | 1992 | 2020 | ||||||||
|
RUNX family transcription factor 1 | 0.425 | 0.808 | 0.65 |
|
disease | 0.800 | strong | 0.985 | 1 | 0 | 1991 | 2020 | ||||||||
|
telomerase reverse transcriptase | 0.374 | 0.846 | 0.99 |
|
disease | 0.700 | strong | 1.000 | 3 | 0 | 2003 | 2018 | ||||||||
|
FA complementation group F | 0.535 | 0.731 | 0.46 |
|
disease | 0.510 | strong | 1.000 | 1 | 0 | 2003 | 2017 | ||||||||
|
BLM RecQ like helicase | 0.535 | 0.808 | 1.5E-15 |
|
disease | 0.300 | strong | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
nuclear receptor binding SET domain protein 1 | 0.505 | 0.769 | 1.00 |
|
disease | 0.700 | strong | 1.000 | 1 | 0 | 2002 | 2019 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
disease | 0.330 | strong | 1.000 | 1 | 0 | 2002 | 2017 | ||||||||
|
X-ray repair cross complementing 2 | 0.512 | 0.731 | 4.0E-07 |
|
disease | 0.300 | strong | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
partner and localizer of BRCA2 | 0.485 | 0.769 | 3.0E-19 |
|
disease | 0.500 | strong | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
CST telomere replication complex component 1 | 0.601 | 0.538 | 1.6E-11 |
|
disease | 0.300 | strong | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
BRCA1 interacting protein C-terminal helicase 1 | 0.507 | 0.731 | 6.2E-17 |
|
disease | 0.500 | strong | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
SLX4 structure-specific endonuclease subunit | 0.565 | 0.731 | 1.6E-22 |
|
disease | 0.300 | strong | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
RAD51 paralog C | 0.533 | 0.692 | 6.2E-14 |
|
disease | 0.300 | moderate | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
FA complementation group A | 0.505 | 0.731 | 1.6E-68 |
|
disease | 0.530 | strong | 1.000 | 1 | 0 | 2002 | 2017 | ||||||||
|
FA complementation group M | 0.543 | 0.731 | 2.4E-15 |
|
disease | 0.300 | moderate | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
FA complementation group G | 0.556 | 0.769 | 2.5E-14 |
|
disease | 0.510 | strong | 1.000 | 1 | 0 | 2016 | 2017 | ||||||||
|
FA complementation group E | 0.553 | 0.808 | 1.5E-06 |
|
disease | 0.500 | strong | 1.000 | 1 | 0 | 2017 | 2017 |