| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
cyclin dependent kinase inhibitor 2A | 0.300 | 0.885 | 0.39 |
|
disease | 0.200 | None | 0.941 | 0 | 0 | 1995 | 2015 | ||||||||
|
PMS1 homolog 2, mismatch repair system component | 0.484 | 0.808 | 4.5E-27 |
|
disease | 0.200 | None | 1.000 | 0 | 0 | 2011 | 2019 | ||||||||
|
protein kinase cAMP-dependent type I regulatory subunit alpha | 0.401 | 0.846 | 1.00 |
|
disease | 0.110 | None | 1.000 | 0 | 0 | 2015 | 2015 | ||||||||
|
ribosomal protein S19 | 0.480 | 0.846 | 0.92 |
|
disease | 0.100 | None | 0 | 0 | |||||||||||
|
bone morphogenetic protein receptor type 1A | 0.522 | 0.731 | 0.90 |
|
disease | 0.120 | None | 1.000 | 0 | 0 | 2008 | 2010 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
disease | 0.200 | None | 1.000 | 0 | 0 | 1998 | 2019 | ||||||||
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
disease | 0.140 | None | 1.000 | 0 | 0 | 2004 | 2019 | ||||||||
|
BUB1 mitotic checkpoint serine/threonine kinase | 0.528 | 0.731 | 4.9E-09 |
|
disease | 0.110 | None | < 0.001 | 0 | 0 | 2000 | 2000 | ||||||||
|
BUB1 mitotic checkpoint serine/threonine kinase B | 0.502 | 0.808 | 7.0E-10 |
|
disease | 0.100 | None | 0 | 0 | |||||||||||
|
transforming growth factor beta receptor 2 | 0.413 | 0.846 | 0.13 |
|
disease | 0.500 | None | 1.000 | 0 | 0 | 1995 | 2017 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.500 | None | 0.966 | 0 | 0 | 1991 | 2020 | ||||||||
|
collagen type XIV alpha 1 chain | 0.674 | 0.615 | 1.4E-14 |
|
disease | 0.100 | None | 0 | 0 | |||||||||||
|
alpha and gamma adaptin binding protein | 0.695 | 0.538 | 3.9E-07 |
|
disease | 0.100 | None | 0 | 0 | |||||||||||
|
partner and localizer of BRCA2 | 0.485 | 0.769 | 3.0E-19 |
|
disease | 0.100 | None | 0 | 0 | |||||||||||
|
axin 2 | 0.507 | 0.692 | 0.57 |
|
disease | 0.470 | None | 1.000 | 0 | 0 | 2001 | 2018 | ||||||||
|
BUB3 mitotic checkpoint protein | 0.588 | 0.615 | 0.81 |
|
disease | 0.100 | None | 0 | 0 | |||||||||||
|
thyroid hormone receptor interactor 13 | 0.559 | 0.654 | 1.00 |
|
disease | 0.100 | None | 0 | 0 | |||||||||||
|
multiple inositol-polyphosphate phosphatase 1 | 0.705 | 0.462 | 4.5E-04 |
|
disease | 0.100 | None | 0 | 0 | |||||||||||
|
PMS1 homolog 1, mismatch repair system component | 0.569 | 0.654 | 1.3E-17 |
|
disease | 0.100 | None | 0 | 0 | |||||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.200 | None | 1.000 | 0 | 0 | 2000 | 2019 | ||||||||
|
FANCD2 and FANCI associated nuclease 1 | 0.610 | 0.577 | 1.7E-25 |
|
disease | 0.100 | None | 0 | 0 | |||||||||||
|
palladin, cytoskeletal associated protein | 0.628 | 0.615 | 5.3E-06 |
|
disease | 0.110 | None | 1.000 | 0 | 0 | 2010 | 2010 | ||||||||
|
forkhead box E1 | 0.573 | 0.731 | 0.79 |
|
disease | 0.100 | None | 0 | 0 | |||||||||||
|
gremlin 1, DAN family BMP antagonist | 0.508 | 0.808 | 0.47 |
|
disease | 0.130 | None | 1.000 | 0 | 0 | 2014 | 2019 | ||||||||
|
mutL homolog 3 | 0.582 | 0.538 | 4.9E-08 |
|
disease | 0.100 | None | 0 | 0 |