| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
ATM serine/threonine kinase | 0.374 | 0.885 | 5.6E-47 |
|
disease | 0.600 | None | 0 | 0 | |||||||||||
|
PMS1 homolog 2, mismatch repair system component | 0.484 | 0.808 | 4.5E-27 |
|
disease | 0.310 | None | 1.000 | 0 | 0 | 2010 | 2010 | ||||||||
|
DNA polymerase epsilon, catalytic subunit | 0.526 | 0.731 | 8.0E-27 |
|
disease | 0.300 | None | 0 | 0 | |||||||||||
|
mutY DNA glycosylase | 0.521 | 0.769 | 1.3E-18 |
|
disease | 0.300 | None | 0 | 0 | |||||||||||
|
PMS1 homolog 1, mismatch repair system component | 0.569 | 0.654 | 1.3E-17 |
|
disease | 0.300 | None | 0 | 0 | |||||||||||
|
MCC regulator of WNT signaling pathway | 0.568 | 0.731 | 4.7E-16 |
|
disease | 0.300 | None | 0 | 0 | |||||||||||
|
platelet derived growth factor receptor like | 0.769 | 0.385 | 1.2E-14 |
|
disease | 0.300 | None | 0 | 0 | |||||||||||
|
mutL homolog 3 | 0.582 | 0.538 | 4.9E-08 |
|
disease | 0.300 | None | 0 | 0 | |||||||||||
|
neurotrophic receptor tyrosine kinase 1 | 0.422 | 0.808 | 2.0E-06 |
|
disease | 0.300 | None | 0 | 0 | |||||||||||
|
fibroblast growth factor receptor 3 | 0.391 | 0.846 | 1.6E-05 |
|
disease | 0.500 | None | 0 | 0 | |||||||||||
|
mutL homolog 1 | 0.399 | 0.808 | 3.4E-05 |
|
disease | 0.420 | None | 1.000 | 0 | 0 | 2011 | 2019 | ||||||||
|
mutS homolog 6 | 0.462 | 0.731 | 3.7E-05 |
|
disease | 0.340 | None | 1.000 | 0 | 0 | 2010 | 2020 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.400 | None | 0.950 | 0 | 0 | 1993 | 2019 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
disease | 0.350 | None | 1.000 | 0 | 0 | 1995 | 2016 | ||||||||
|
HRas proto-oncogene, GTPase | 0.378 | 0.885 | 8.0E-02 |
|
disease | 0.330 | None | 1.000 | 0 | 0 | 1993 | 2017 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.310 | None | 1.000 | 0 | 0 | 2017 | 2017 | ||||||||
|
BCL2 associated X, apoptosis regulator | 0.417 | 0.885 | 0.32 |
|
disease | 0.310 | None | 1.000 | 0 | 0 | 2002 | 2002 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
disease | 0.400 | None | 0.923 | 0 | 0 | 1993 | 2018 | ||||||||
|
axin 1 | 0.559 | 0.577 | 0.41 |
|
disease | 0.300 | None | 0 | 0 | |||||||||||
|
NRAS proto-oncogene, GTPase | 0.390 | 0.808 | 0.49 |
|
disease | 0.300 | None | 0 | 0 | |||||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.400 | None | 0.905 | 0 | 0 | 1994 | 2019 | ||||||||
|
axin 2 | 0.507 | 0.692 | 0.57 |
|
disease | 0.300 | None | 0 | 0 | |||||||||||
|
AKT serine/threonine kinase 2 | 0.474 | 0.769 | 0.64 |
|
disease | 0.300 | None | 0 | 0 | |||||||||||
|
ring finger protein 43 | 0.584 | 0.577 | 0.73 |
|
disease | 0.300 | None | 0 | 0 | |||||||||||
|
folliculin | 0.537 | 0.885 | 0.79 |
|
disease | 0.300 | None | 0 | 0 |