| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
WRN RecQ like helicase | 0.524 | 0.808 | 2.6E-34 |
|
group | 0.400 | None | 1.000 | 0 | 0 | 1999 | 2019 | ||||||||
|
mutS homolog 3 | 0.474 | 0.769 | 7.4E-31 |
|
group | 0.400 | None | 0.903 | 0 | 0 | 1998 | 2019 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
group | 0.600 | None | 0.968 | 0 | 0 | 1993 | 2020 | ||||||||
|
dihydropyrimidine dehydrogenase | 0.493 | 0.846 | 3.4E-22 |
|
group | 0.400 | None | 1.000 | 0 | 0 | 1997 | 2019 | ||||||||
|
BLM RecQ like helicase | 0.535 | 0.808 | 1.5E-15 |
|
group | 0.400 | None | 0.979 | 0 | 0 | 1999 | 2019 | ||||||||
|
erb-b2 receptor tyrosine kinase 3 | 0.448 | 0.808 | 1.7E-15 |
|
group | 0.400 | None | 0.977 | 0 | 0 | 1992 | 2020 | ||||||||
|
ATR serine/threonine kinase | 0.456 | 0.923 | 3.5E-09 |
|
group | 0.400 | None | 0.965 | 0 | 0 | 1999 | 2020 | ||||||||
|
cytokine receptor like factor 2 | 0.615 | 0.538 | 3.3E-07 |
|
group | 0.320 | None | 1.000 | 0 | 0 | 2010 | 2019 | ||||||||
|
5'-nucleotidase, cytosolic II | 0.537 | 0.846 | 2.1E-06 |
|
group | 0.400 | None | 0.900 | 0 | 0 | 2003 | 2019 | ||||||||
|
UDP glucuronosyltransferase family 1 member A1 | 0.464 | 0.769 | 3.3E-06 |
|
group | 0.400 | None | 1.000 | 0 | 0 | 2000 | 2019 | ||||||||
|
thiopurine S-methyltransferase | 0.593 | 0.692 | 7.1E-06 |
|
group | 0.400 | None | 0.833 | 0 | 0 | 2000 | 2018 | ||||||||
|
EPH receptor A3 | 0.497 | 0.692 | 1.2E-05 |
|
group | 0.400 | None | 0.933 | 0 | 0 | 2010 | 2019 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
group | 0.600 | None | 0.972 | 0 | 0 | 1987 | 2020 | ||||||||
|
cyclin dependent kinase inhibitor 1A | 0.403 | 0.769 | 1.9E-03 |
|
group | 0.400 | None | 0.987 | 0 | 0 | 1994 | 2019 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
group | 0.400 | None | 0.969 | 0 | 0 | 1985 | 2020 | ||||||||
|
cyclin dependent kinase inhibitor 2B | 0.417 | 0.769 | 7.3E-03 |
|
group | 0.400 | None | 0.947 | 0 | 0 | 1995 | 2018 | ||||||||
|
CD274 molecule | 0.324 | 0.923 | 1.9E-02 |
|
group | 0.400 | None | 0.979 | 0 | 0 | 2003 | 2020 | ||||||||
|
cyclin dependent kinase 4 | 0.412 | 0.808 | 6.3E-02 |
|
group | 0.400 | None | 0.966 | 0 | 0 | 1995 | 2019 | ||||||||
|
von Hippel-Lindau tumor suppressor | 0.443 | 0.846 | 8.0E-02 |
|
group | 0.400 | None | 0.959 | 0 | 0 | 1989 | 2019 | ||||||||
|
HRas proto-oncogene, GTPase | 0.378 | 0.885 | 8.0E-02 |
|
group | 0.400 | None | 0.955 | 0 | 0 | 1983 | 2019 | ||||||||
|
colony stimulating factor 1 receptor | 0.448 | 0.808 | 0.13 |
|
group | 0.600 | None | 1.000 | 0 | 0 | 1992 | 2020 | ||||||||
|
myogenic differentiation 1 | 0.569 | 0.654 | 0.15 |
|
group | 0.370 | None | 1.000 | 0 | 0 | 2001 | 2020 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
group | 0.400 | None | 0.977 | 0 | 0 | 1997 | 2020 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
group | 0.400 | None | 0.977 | 0 | 0 | 1987 | 2020 | ||||||||
|
cyclin dependent kinase inhibitor 2A | 0.300 | 0.885 | 0.39 |
|
group | 0.600 | None | 0.946 | 0 | 0 | 1994 | 2020 |