Source: RGD

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.200 None 1.000 1 0 2004 2004
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.500 None 1.000 1 0 2004 2004
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.200 None 1.000 1 0 2004 2004
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.305 0.923 1.9E-17
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.200 None 1.000 1 0 2006 2006
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.200 None 1.000 1 0 2005 2005
Entrez Id: 1636
Gene Symbol: ACE
ACE
angiotensin I converting enzyme 0.328 0.923 1.0E-37
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.220 None 1.000 1 0 2004 2014
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
mitogen-activated protein kinase 1 0.330 0.923 1.00
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.210 None 1.000 1 0 2005 2009
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.200 None 1.000 1 0 2005 2005
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
mechanistic target of rapamycin kinase 0.343 0.885 1.00
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.200 None 1.000 1 0 2010 2010
Entrez Id: 4609
Gene Symbol: MYC
MYC
MYC proto-oncogene, bHLH transcription factor 0.344 0.923 1.00
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.200 None 1.000 1 0 2013 2013
Entrez Id: 960
Gene Symbol: CD44
CD44
CD44 molecule (Indian blood group) 0.363 0.962 2.4E-07
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.200 None 1.000 1 0 2008 2008
Entrez Id: 183
Gene Symbol: AGT
AGT
angiotensinogen 0.367 0.923 5.0E-08
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.500 None 1.000 2 0 2001 2019
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
nitric oxide synthase 3 0.378 0.885 6.7E-07
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.510 None 1.000 2 0 2001 2018
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
sirtuin 1 0.378 0.885 8.7E-02
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.200 None 1.000 1 0 2014 2014
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
endothelin 1 0.380 0.846 0.46
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.510 None 1.000 1 0 1995 2012
Entrez Id: 4233
Gene Symbol: MET
MET
MET proto-oncogene, receptor tyrosine kinase 0.380 0.846 0.97
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.200 None 1.000 1 0 1999 1999
Entrez Id: 2247
Gene Symbol: FGF2
FGF2
fibroblast growth factor 2 0.383 0.923 1.8E-02
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.500 None 1.000 1 0 1999 2008
Entrez Id: 857
Gene Symbol: CAV1
CAV1
caveolin 1 0.388 0.885 8.3E-03
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.500 None 1.000 1 0 2006 2006
Entrez Id: 5970
Gene Symbol: RELA
RELA
RELA proto-oncogene, NF-kB subunit 0.406 0.885 1.00
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.200 None 1.000 2 0 2005 2005
Entrez Id: 952
Gene Symbol: CD38
CD38
CD38 molecule 0.407 0.885 2.3E-06
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.200 None 1.000 1 0 2009 2009
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
nitric oxide synthase 1 0.408 0.885 1.00
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.200 None 1.000 1 0 2007 2007
Entrez Id: 5159
Gene Symbol: PDGFRB
PDGFRB
platelet derived growth factor receptor beta 0.416 0.846 0.90
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.200 None 1.000 1 0 2002 2002
Entrez Id: 6271
Gene Symbol: S100A1
S100A1
S100 calcium binding protein A1 0.421 0.846 6.0E-03
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.200 None 1.000 1 0 2003 2003
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
angiotensin II receptor type 1 0.423 0.846 5.3E-04
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.230 None 1.000 2 0 1998 2011
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
plasminogen activator, urokinase 0.425 0.923 2.3E-06
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
phenotype 0.200 None 1.000 1 0 2012 2012