Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 27328
Gene Symbol: PCDH11X
PCDH11X
protocadherin 11 X-linked 0.729 0.308 1.6E-02
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.420 None 1.000 1 0 2009 2011
Entrez Id: 590
Gene Symbol: BCHE
BCHE
butyrylcholinesterase 0.447 0.923 1.1E-13
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 0.962 7 0 1995 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 0.963 6 0 1998 2020
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.324 0.962 1.00
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 0.944 5 0 1999 2019
Entrez Id: 1139
Gene Symbol: CHRNA7
CHRNA7
cholinergic receptor nicotinic alpha 7 subunit 0.532 0.654 4.2E-04
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 1.000 5 0 2001 2017
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 0.938 3 0 1993 2019
Entrez Id: 1718
Gene Symbol: DHCR24
DHCR24
24-dehydrocholesterol reductase 0.498 0.769 3.1E-02
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 0.958 3 0 2000 2019
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
heme oxygenase 1 0.381 0.923 9.7E-03
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 0.920 3 0 1995 2020
Entrez Id: 10858
Gene Symbol: CYP46A1
CYP46A1
cytochrome P450 family 46 subfamily A member 1 0.659 0.500 0.99
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 0.953 3 0 2000 2019
Entrez Id: 5621
Gene Symbol: PRNP
PRNP
prion protein 0.445 0.923 6.3E-04
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 0.902 3 0 1986 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 0.919 3 0 2005 2020
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
insulin like growth factor 1 0.318 0.885 0.27
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 1.000 2 0 2000 2020
Entrez Id: 1471
Gene Symbol: CST3
CST3
cystatin C 0.436 0.808 3.9E-03
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 0.935 2 0 1988 2019
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
peroxisome proliferator activated receptor gamma 0.358 0.885 2.9E-02
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 0.907 2 0 2000 2019
Entrez Id: 4129
Gene Symbol: MAOB
MAOB
monoamine oxidase B 0.533 0.808 1.00
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 1.000 1 0 1994 2020
Entrez Id: 43
Gene Symbol: ACHE
ACHE
acetylcholinesterase (Cartwright blood group) 0.445 0.885 1.00
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 0.985 1 0 1991 2020
Entrez Id: 1808
Gene Symbol: DPYSL2
DPYSL2
dihydropyrimidinase like 2 0.585 0.692 0.99
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 0.947 1 0 1999 2020
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
cytochrome P450 family 2 subfamily D member 6 0.437 0.885 1.1E-25
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 0.909 1 0 1995 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
methylenetetrahydrofolate reductase 0.337 0.885 3.2E-10
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 0.868 1 0 1999 2018
Entrez Id: 23385
Gene Symbol: NCSTN
NCSTN
nicastrin 0.666 0.462 1.00
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 1.000 1 0 2001 2020
Entrez Id: 406938
Gene Symbol: MIR146A
MIR146A
microRNA 146a 0.398 0.885
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 1.000 1 0 2008 2019
Entrez Id: 5649
Gene Symbol: RELN
RELN
reelin 0.515 0.731 1.00
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 1.000 1 0 2002 2019
Entrez Id: 7019
Gene Symbol: TFAM
TFAM
transcription factor A, mitochondrial 0.529 0.731 0.17
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.400 None 0.900 1 0 2004 2019
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
superoxide dismutase 2 0.379 0.923 0.15
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.380 None 0.889 1 0 2001 2018
Entrez Id: 7018
Gene Symbol: TF
TF
transferrin 0.527 0.846 4.1E-08
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.350 None 1.000 2 0 2002 2012