Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.982 5 0 1994 2020
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
hypoxia inducible factor 1 subunit alpha 0.327 0.923 0.98
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.100 None 0.986 5 0 2002 2020
Entrez Id: 389
Gene Symbol: RHOC
RHOC
ras homolog family member C 0.641 0.308 0.77
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 1.000 5 0 2003 2019
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
C-X-C motif chemokine ligand 8 0.310 0.962 2.7E-04
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.100 None 0.986 5 0 1994 2020
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.324 0.962 1.00
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.962 5 0 1992 2020
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.976 4 0 1997 2020
Entrez Id: 3691
Gene Symbol: ITGB4
ITGB4
integrin subunit beta 4 0.525 0.731 9.5E-19
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.100 None 1.000 4 0 2002 2020
Entrez Id: 4323
Gene Symbol: MMP14
MMP14
matrix metallopeptidase 14 0.447 0.769 1.00
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.100 None 0.989 4 0 1996 2020
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
cellular communication network factor 2 0.399 0.846 5.0E-04
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.100 None 1.000 4 0 2004 2020
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
secreted phosphoprotein 1 0.353 0.885 2.1E-06
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.989 4 0 1996 2020
Entrez Id: 960
Gene Symbol: CD44
CD44
CD44 molecule (Indian blood group) 0.363 0.962 2.4E-07
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.979 4 0 1990 2020
Entrez Id: 3082
Gene Symbol: HGF
HGF
hepatocyte growth factor 0.374 0.885 1.00
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.986 4 0 1993 2019
Entrez Id: 7074
Gene Symbol: TIAM1
TIAM1
TIAM Rac1 associated GEF 1 0.579 0.731 0.96
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.100 None 0.938 4 0 2003 2019
Entrez Id: 5329
Gene Symbol: PLAUR
PLAUR
plasminogen activator, urokinase receptor 0.536 0.731 5.3E-03
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 1.000 4 0 1998 2017
Entrez Id: 2324
Gene Symbol: FLT4
FLT4
fms related receptor tyrosine kinase 4 0.457 0.808 1.00
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.100 None 0.970 4 0 2000 2019
Entrez Id: 25855
Gene Symbol: BRMS1
BRMS1
BRMS1 transcriptional repressor and anoikis regulator 0.597 0.615 1.6E-07
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 1.000 4 0 2000 2019
Entrez Id: 94025
Gene Symbol: MUC16
MUC16
mucin 16, cell surface associated 0.479 0.808 8.3E-112
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.100 None 0.944 4 0 2004 2019
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1
twist family bHLH transcription factor 1 0.397 0.846 0.34
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.980 4 0 2004 2019
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
cyclin dependent kinase inhibitor 1B 0.409 0.769 0.62
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.100 None 0.957 4 0 2000 2019
Entrez Id: 2191
Gene Symbol: FAP
FAP
fibroblast activation protein alpha 0.496 0.808 1.9E-28
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.080 None 1.000 3 0 2003 2019
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
erb-b2 receptor tyrosine kinase 3 0.448 0.808 1.7E-15
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.400 None 0.969 3 0 1998 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1
cyclin D1 0.344 0.923 0.89
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.100 None 0.959 3 0 1996 2019
Entrez Id: 7077
Gene Symbol: TIMP2
TIMP2
TIMP metallopeptidase inhibitor 2 0.425 0.846 0.79
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.100 None 0.953 3 0 1993 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.100 None 0.932 3 0 2003 2020
Entrez Id: 6850
Gene Symbol: SYK
SYK
spleen associated tyrosine kinase 0.475 0.808 1.00
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
phenotype 0.100 None 1.000 3 0 2003 2019