Source: CTD_human

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 324
Gene Symbol: APC
APC
APC regulator of WNT signaling pathway 0.373 0.962 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.900 None 0.982 7 0 1990 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.700 None 0.989 8 0 1991 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.303 0.885 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.700 None 0.985 4 0 1997 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.700 None 1.000 2 0 1996 2016
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
thymidylate synthetase 0.425 0.846 0.72
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.600 None 1.000 11 0 1998 2015
Entrez Id: 1806
Gene Symbol: DPYD
DPYD
dihydropyrimidine dehydrogenase 0.493 0.846 3.4E-22
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.600 None 0.952 5 0 1999 2016
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.500 None 0.978 4 0 2002 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.500 None 0.983 3 0 1990 2019
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
SMAD family member 4 0.401 0.808 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.500 None 1.000 3 0 1996 2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.500 None 0.976 2 0 2003 2019
Entrez Id: 999
Gene Symbol: CDH1
CDH1
cadherin 1 0.401 0.808 0.15
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.500 None 0.950 2 0 1999 2019
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
transcription factor 7 like 2 0.485 0.846 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.490 None 1.000 2 0 2002 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.490 None 1.000 0 0 2004 2019
Entrez Id: 26585
Gene Symbol: GREM1
GREM1
gremlin 1, DAN family BMP antagonist 0.508 0.808 0.47
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.430 None 1.000 2 0 2008 2020
Entrez Id: 894
Gene Symbol: CCND2
CCND2
cyclin D2 0.477 0.808 0.99
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.420 None 1.000 1 0 2011 2019
Entrez Id: 688
Gene Symbol: KLF5
KLF5
Kruppel like factor 5 0.534 0.769 0.82
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.410 None 1.000 1 0 2008 2019
Entrez Id: 4092
Gene Symbol: SMAD7
SMAD7
SMAD family member 7 0.470 0.769 0.55
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.410 None 1.000 1 0 2007 2019
Entrez Id: 652
Gene Symbol: BMP4
BMP4
bone morphogenetic protein 4 0.422 0.808 0.96
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.410 None 1.000 1 0 2008 2019
Entrez Id: 91653
Gene Symbol: BOC
BOC
BOC cell adhesion associated, oncogene regulated 0.666 0.423 1.7E-07
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.410 None 1.000 1 0 2018 2019
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
NRAS proto-oncogene, GTPase 0.390 0.808 0.49
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.410 None 1.000 0 0 2006 2016
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
methylenetetrahydrofolate reductase 0.337 0.885 3.2E-10
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.400 None 1.000 8 0 2002 2014
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.400 None 1.000 6 0 1999 2019
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
mutL homolog 1 0.399 0.808 3.4E-05
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.400 None 1.000 3 0 1997 2019
Entrez Id: 10714
Gene Symbol: POLD3
POLD3
DNA polymerase delta 3, accessory subunit 0.631 0.462 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.400 None 1.000 2 0 2012 2019
Entrez Id: 5426
Gene Symbol: POLE
POLE
DNA polymerase epsilon, catalytic subunit 0.526 0.731 8.0E-27
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.400 None 1.000 2 0 2013 2016