| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
APC regulator of WNT signaling pathway | 0.373 | 0.962 | 1.00 |
|
group | 0.900 | None | 0.982 | 25 | 0 | 1990 | 2019 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
group | 0.700 | None | 0.989 | 35 | 0 | 1991 | 2018 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
group | 0.700 | None | 0.985 | 21 | 0 | 1997 | 2019 | ||||||||
|
matrix metallopeptidase 2 | 0.333 | 0.923 | 0.84 |
|
group | 0.700 | None | 1.000 | 7 | 0 | 1996 | 2016 | ||||||||
|
thymidylate synthetase | 0.425 | 0.846 | 0.72 |
|
group | 0.600 | None | 1.000 | 18 | 0 | 1998 | 2015 | ||||||||
|
dihydropyrimidine dehydrogenase | 0.493 | 0.846 | 3.4E-22 |
|
group | 0.600 | None | 0.952 | 8 | 0 | 1999 | 2016 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
group | 0.500 | None | 0.983 | 41 | 0 | 1990 | 2019 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
group | 0.500 | None | 0.978 | 26 | 0 | 2002 | 2019 | ||||||||
|
cadherin 1 | 0.401 | 0.808 | 0.15 |
|
group | 0.500 | None | 0.950 | 15 | 0 | 1999 | 2019 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
group | 0.500 | None | 0.976 | 15 | 0 | 2003 | 2019 | ||||||||
|
SMAD family member 4 | 0.401 | 0.808 | 1.00 |
|
group | 0.500 | None | 1.000 | 5 | 0 | 1996 | 2016 | ||||||||
|
transcription factor 7 like 2 | 0.485 | 0.846 | 1.00 |
|
group | 0.490 | None | 1.000 | 6 | 0 | 2002 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
group | 0.490 | None | 1.000 | 4 | 0 | 2004 | 2019 | ||||||||
|
Kruppel like factor 5 | 0.534 | 0.769 | 0.82 |
|
group | 0.410 | None | 1.000 | 1 | 0 | 2008 | 2019 | ||||||||
|
SMAD family member 7 | 0.470 | 0.769 | 0.55 |
|
group | 0.410 | None | 1.000 | 1 | 0 | 2007 | 2019 | ||||||||
|
mutL homolog 1 | 0.399 | 0.808 | 3.4E-05 |
|
group | 0.400 | None | 1.000 | 49 | 0 | 1997 | 2019 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
group | 0.400 | None | 1.000 | 22 | 0 | 1999 | 2019 | ||||||||
|
mutS homolog 2 | 0.406 | 0.808 | 0.90 |
|
group | 0.400 | None | 1.000 | 20 | 0 | 1996 | 2019 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
group | 0.400 | None | 1.000 | 13 | 0 | 2002 | 2014 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
group | 0.400 | None | 1.000 | 9 | 0 | 1999 | 2014 | ||||||||
|
BCL2 apoptosis regulator | 0.291 | 0.885 | 0.56 |
|
group | 0.400 | None | 1.000 | 7 | 0 | 1996 | 2018 | ||||||||
|
insulin like growth factor 2 | 0.390 | 0.885 | 4.4E-02 |
|
group | 0.400 | None | 1.000 | 5 | 0 | 1990 | 2017 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
group | 0.390 | None | 1.000 | 3 | 0 | 2003 | 2017 | ||||||||
|
MYC proto-oncogene, bHLH transcription factor | 0.344 | 0.923 | 1.00 |
|
group | 0.390 | None | 1.000 | 3 | 0 | 1990 | 2019 | ||||||||
|
matrix metallopeptidase 1 | 0.385 | 0.885 | 7.7E-18 |
|
group | 0.380 | None | 1.000 | 8 | 0 | 2002 | 2013 |