| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
FA complementation group L | 0.551 | 0.731 | 5.9E-23 |
|
disease | 0.700 | None | 1.000 | 5 | 0 | 2003 | 2020 | ||||||||
|
FA complementation group M | 0.543 | 0.731 | 2.4E-15 |
|
disease | 0.700 | None | 0.941 | 5 | 0 | 2005 | 2019 | ||||||||
|
FA complementation group A | 0.505 | 0.731 | 1.6E-68 |
|
disease | 0.700 | strong | 0.978 | 4 | 0 | 1991 | 2020 | ||||||||
|
FA complementation group C | 0.507 | 0.808 | 2.8E-13 |
|
disease | 0.700 | strong | 1.000 | 4 | 0 | 1992 | 2019 | ||||||||
|
SLX4 structure-specific endonuclease subunit | 0.565 | 0.731 | 1.6E-22 |
|
disease | 0.700 | strong | 1.000 | 3 | 0 | 2009 | 2017 | ||||||||
|
FA complementation group G | 0.556 | 0.769 | 2.5E-14 |
|
disease | 0.700 | strong | 0.935 | 3 | 0 | 1998 | 2017 | ||||||||
|
FA complementation group D2 | 0.479 | 0.885 | 1.1E-30 |
|
disease | 0.700 | strong | 0.972 | 3 | 0 | 1998 | 2020 | ||||||||
|
BRCA1 interacting protein C-terminal helicase 1 | 0.507 | 0.731 | 6.2E-17 |
|
disease | 0.700 | strong | 0.957 | 2 | 0 | 2005 | 2019 | ||||||||
|
RAD51 paralog C | 0.533 | 0.692 | 6.2E-14 |
|
disease | 0.600 | moderate | 1.000 | 4 | 0 | 2009 | 2019 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
disease | 0.600 | None | 1.000 | 3 | 0 | 2001 | 2020 | ||||||||
|
RAD51 recombinase | 0.447 | 0.846 | 2.7E-02 |
|
disease | 0.600 | moderate | 1.000 | 1 | 0 | 2002 | 2019 | ||||||||
|
ERCC excision repair 4, endonuclease catalytic subunit | 0.468 | 0.846 | 1.4E-12 |
|
disease | 0.600 | strong | 0.917 | 1 | 0 | 2007 | 2018 | ||||||||
|
ubiquitin conjugating enzyme E2 T | 0.550 | 0.731 | 1.1E-05 |
|
disease | 0.590 | strong | 1.000 | 1 | 0 | 2006 | 2019 | ||||||||
|
X-ray repair cross complementing 2 | 0.512 | 0.731 | 4.0E-07 |
|
disease | 0.540 | strong | 1.000 | 1 | 0 | 2012 | 2019 | ||||||||
|
mitotic arrest deficient 2 like 2 | 0.547 | 0.731 | 8.2E-02 |
|
disease | 0.510 | strong | 1.000 | 1 | 0 | 2016 | 2017 | ||||||||
|
FA complementation group I | 0.543 | 0.731 | 8.9E-37 |
|
disease | 0.500 | strong | 1.000 | 4 | 0 | 2001 | 2019 | ||||||||
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
disease | 0.500 | strong | 0.970 | 3 | 0 | 1998 | 2019 | ||||||||
|
FA complementation group F | 0.535 | 0.731 | 0.46 |
|
disease | 0.500 | strong | 1.000 | 2 | 0 | 2000 | 2019 | ||||||||
|
FA complementation group B | 0.468 | 0.769 | 1.00 |
|
disease | 0.480 | strong | 1.000 | 1 | 0 | 2002 | 2019 | ||||||||
|
partner and localizer of BRCA2 | 0.485 | 0.769 | 3.0E-19 |
|
disease | 0.400 | strong | 1.000 | 3 | 0 | 2007 | 2019 | ||||||||
|
FA complementation group E | 0.553 | 0.808 | 1.5E-06 |
|
disease | 0.400 | strong | 0.933 | 3 | 0 | 1995 | 2020 | ||||||||
|
ERCC excision repair 1, endonuclease non-catalytic subunit | 0.445 | 0.846 | 1.6E-07 |
|
disease | 0.320 | strong | 1.000 | 1 | 0 | 2007 | 2009 |