Source: ANIMAL_MODELS

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5465
Gene Symbol: PPARA
PPARA
peroxisome proliferator activated receptor alpha 0.432 0.885 3.0E-02
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.530 None 1.000 1 0 2006 2018
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
cytochrome P450 family 2 subfamily E member 1 0.459 0.885 8.1E-09
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.520 None 1.000 1 0 2009 2018
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
sirtuin 1 0.378 0.885 8.7E-02
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.260 None 1.000 0 0 2012 2019
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
peroxisome proliferator activated receptor gamma 0.358 0.885 2.9E-02
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.210 None 1.000 1 0 2004 2010
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.210 None 1.000 1 0 2009 2009
Entrez Id: 84649
Gene Symbol: DGAT2
DGAT2
diacylglycerol O-acyltransferase 2 0.686 0.423 8.4E-12
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.210 None 1.000 1 0 2007 2010
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
adiponectin, C1Q and collagen domain containing 0.376 0.885 4.6E-09
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.210 None 1.000 1 0 2006 2009
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
low density lipoprotein receptor 0.449 0.885 9.8E-24
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 10 0 1997 2011
Entrez Id: 3643
Gene Symbol: INSR
INSR
insulin receptor 0.432 0.846 3.6E-05
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 3 0 2012 2019
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
galectin 3 0.392 0.846 2.3E-05
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 2 0 2006 2008
Entrez Id: 4040
Gene Symbol: LRP6
LRP6
LDL receptor related protein 6 0.536 0.808 0.70
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 2 0 2014 2015
Entrez Id: 4160
Gene Symbol: MC4R
MC4R
melanocortin 4 receptor 0.535 0.692 9.2E-04
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 2 0 2005 2011
Entrez Id: 1508
Gene Symbol: CTSB
CTSB
cathepsin B 0.457 0.846 5.9E-11
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 2 0 2007 2008
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
PPARG coactivator 1 alpha 0.453 0.885 1.00
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 2 0 2012 2013
Entrez Id: 3952
Gene Symbol: LEP
LEP
leptin 0.349 0.846 0.46
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 2 0 2011 2015
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
signal transducer and activator of transcription 4 0.471 0.769 0.77
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2008 2008
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
serpin family E member 1 0.359 0.885 4.4E-02
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2014 2014
Entrez Id: 5009
Gene Symbol: OTC
OTC
ornithine carbamoyltransferase 0.565 0.846 0.87
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2009 2009
Entrez Id: 847
Gene Symbol: CAT
CAT
catalase 0.359 0.962 1.6E-10
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2011 2011
Entrez Id: 8714
Gene Symbol: ABCC3
ABCC3
ATP binding cassette subfamily C member 3 0.517 0.769 1.2E-26
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2007 2007
Entrez Id: 4976
Gene Symbol: OPA1
OPA1
OPA1 mitochondrial dynamin like GTPase 0.510 0.846 0.99
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2014 2014
Entrez Id: 9927
Gene Symbol: MFN2
MFN2
mitofusin 2 0.471 0.846 0.99
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2014 2014
Entrez Id: 51024
Gene Symbol: FIS1
FIS1
fission, mitochondrial 1 0.663 0.769 1.3E-05
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2014 2014
Entrez Id: 5176
Gene Symbol: SERPINF1
SERPINF1
serpin family F member 1 0.460 0.846 7.8E-08
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2009 2009
Entrez Id: 7351
Gene Symbol: UCP2
UCP2
uncoupling protein 2 0.493 0.808 1.5E-10
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
disease 0.200 None 1.000 1 0 2011 2011