Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.700 None 0.975 17 0 1988 2020
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.500 None 0.977 5 0 1997 2020
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
mechanistic target of rapamycin kinase 0.343 0.885 1.00
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.500 None 0.967 2 0 2005 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.400 None 0.976 15 0 1990 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.400 None 0.994 6 0 1992 2020
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
O-6-methylguanine-DNA methyltransferase 0.412 0.885 1.2E-07
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.400 None 0.970 5 0 1992 2020
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.305 0.923 1.9E-17
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.400 None 1.000 4 0 1996 2019
Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1
chitinase 3 like 1 0.419 0.885 1.1E-05
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.400 None 0.966 3 0 2003 2020
Entrez Id: 8842
Gene Symbol: PROM1
PROM1
prominin 1 0.410 0.846 1.9E-22
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.400 None 0.991 3 0 2006 2020
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
hypoxia inducible factor 1 subunit alpha 0.327 0.923 0.98
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.400 None 1.000 2 0 2000 2019
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
C-X-C motif chemokine ligand 8 0.310 0.962 2.7E-04
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.400 None 1.000 2 0 1991 2019
Entrez Id: 1508
Gene Symbol: CTSB
CTSB
cathepsin B 0.457 0.846 5.9E-11
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.400 None 1.000 2 0 1995 2018
Entrez Id: 4609
Gene Symbol: MYC
MYC
MYC proto-oncogene, bHLH transcription factor 0.344 0.923 1.00
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.400 None 1.000 1 0 1986 2019
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
platelet derived growth factor receptor alpha 0.415 0.808 1.00
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.400 None 0.974 1 0 1995 2020
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.400 None 0.977 1 0 1998 2019
Entrez Id: 4233
Gene Symbol: MET
MET
MET proto-oncogene, receptor tyrosine kinase 0.380 0.846 0.97
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.400 None 0.979 1 0 1993 2020
Entrez Id: 5747
Gene Symbol: PTK2
PTK2
protein tyrosine kinase 2 0.497 0.808 1.00
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.370 None 1.000 2 0 2002 2019
Entrez Id: 7490
Gene Symbol: WT1
WT1
WT1 transcription factor 0.422 0.808 1.00
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.350 None 1.000 1 0 2004 2014
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
glutathione S-transferase theta 1 0.393 0.923 1.5E-04
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.320 None 1.000 1 0 2004 2006
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.300 None 0.962 2 0 1999 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.200 None 0.944 3 0 2000 2020
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
fibroblast growth factor receptor 1 0.362 0.885 1.00
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.200 None 0.882 2 0 1994 2019
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
isocitrate dehydrogenase (NADP(+)) 1 0.424 0.808 2.6E-12
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.200 None 0.975 2 0 2008 2020
Entrez Id: 472
Gene Symbol: ATM
ATM
ATM serine/threonine kinase 0.374 0.885 5.6E-47
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.200 None 1.000 1 0 2000 2019
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
mutS homolog 2 0.406 0.808 0.90
CUI: C0017636
Disease: Glioblastoma
Glioblastoma
disease 0.190 None 1.000 3 0 2003 2019