Source: ANIMAL_MODELS

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6336
Gene Symbol: SCN10A
SCN10A
sodium voltage-gated channel alpha subunit 10 0.566 0.692 9.9E-38
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.620 None 1.000 1 0 2006 2017
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.600 None 1.000 3 0 1995 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.600 None 1.000 3 0 1995 2020
Entrez Id: 4803
Gene Symbol: NGF
NGF
nerve growth factor 0.391 0.885 0.82
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.600 None 0.957 3 0 1998 2020
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.600 None 1.000 1 0 2004 2020
Entrez Id: 7442
Gene Symbol: TRPV1
TRPV1
transient receptor potential cation channel subfamily V member 1 0.446 0.885 1.0E-16
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.600 None 1.000 1 0 2002 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.580 None 1.000 2 0 1995 2019
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
C-C motif chemokine ligand 2 0.321 0.962 0.61
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.570 None 1.000 3 0 2007 2019
Entrez Id: 8989
Gene Symbol: TRPA1
TRPA1
transient receptor potential cation channel subfamily A member 1 0.546 0.846 7.2E-35
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.570 None 1.000 1 0 2008 2019
Entrez Id: 2904
Gene Symbol: GRIN2B
GRIN2B
glutamate ionotropic receptor NMDA type subunit 2B 0.510 0.692 1.00
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.560 None 1.000 1 0 2009 2020
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
kininogen 1 0.481 0.885 3.2E-10
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.560 None 0.958 1 0 1988 2019
Entrez Id: 796
Gene Symbol: CALCA
CALCA
calcitonin related polypeptide alpha 0.416 0.923 1.6E-02
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.540 None 1.000 1 0 2003 2019
Entrez Id: 199
Gene Symbol: AIF1
AIF1
allograft inflammatory factor 1 0.521 0.808 1.9E-06
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.540 None 1.000 1 0 2007 2020
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
interleukin 1 receptor antagonist 0.373 0.923 3.1E-02
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.520 None 1.000 2 0 1996 2019
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
high mobility group box 1 0.368 0.923 0.82
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.520 None 1.000 2 0 2014 2019
Entrez Id: 5742
Gene Symbol: PTGS1
PTGS1
prostaglandin-endoperoxide synthase 1 0.460 0.885 6.2E-07
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.520 None 1.000 1 0 2007 2020
Entrez Id: 3586
Gene Symbol: IL10
IL10
interleukin 10 0.281 0.923 5.9E-03
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.510 None 1.000 2 0 1995 2017
Entrez Id: 887
Gene Symbol: CCKBR
CCKBR
cholecystokinin B receptor 0.573 0.615 2.1E-06
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.510 None 1.000 1 0 2002 2019
Entrez Id: 133
Gene Symbol: ADM
ADM
adrenomedullin 0.436 0.808 4.1E-02
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.510 None 1.000 1 0 2006 2017
Entrez Id: 2353
Gene Symbol: FOS
FOS
Fos proto-oncogene, AP-1 transcription factor subunit 0.411 0.885 0.26
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.510 None 1.000 1 0 2012 2018
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2
bradykinin receptor B2 0.585 0.808 0.12
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.500 None 1.000 2 0 1999 2010
Entrez Id: 177
Gene Symbol: AGER
AGER
advanced glycosylation end-product specific receptor 0.420 0.885 6.4E-16
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.500 None 1.000 2 0 2014 2014
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
matrix metallopeptidase 3 0.408 0.885 5.7E-15
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.500 None 1.000 1 0 2008 2012
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
5-hydroxytryptamine receptor 2A 0.473 0.846 0.51
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.500 None 1.000 1 0 2008 2010
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
glial fibrillary acidic protein 0.421 0.885 1.5E-06
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
phenotype 0.500 None 1.000 1 0 2005 2016