Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
solute carrier family 6 member 4 0.429 0.808 0.25
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.530 None 1.000 3 0 2001 2009
Entrez Id: 4879
Gene Symbol: NPPB
NPPB
natriuretic peptide B 0.513 0.808 9.9E-06
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.530 None 1.000 1 0 2005 2011
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
endothelin 1 0.380 0.846 0.46
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.530 None 1.000 1 0 1994 2010
Entrez Id: 94
Gene Symbol: ACVRL1
ACVRL1
activin A receptor like type 1 0.493 0.769 9.7E-04
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.510 None 1.000 1 0 2003 2016
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
nitric oxide synthase 3 0.378 0.885 6.7E-07
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 None 1.000 4 0 2006 2018
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5
arachidonate 5-lipoxygenase 0.447 0.885 1.2E-06
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 None 1.000 3 0 1996 2019
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
C-C motif chemokine ligand 2 0.321 0.962 0.61
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 None 1.000 2 0 1998 2018
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
hypoxia inducible factor 1 subunit alpha 0.327 0.923 0.98
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 None 1.000 2 0 2005 2010
Entrez Id: 1910
Gene Symbol: EDNRB
EDNRB
endothelin receptor type B 0.470 0.846 9.2E-03
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 None 1.000 2 0 2004 2008
Entrez Id: 3741
Gene Symbol: KCNA5
KCNA5
potassium voltage-gated channel subfamily A member 5 0.606 0.500 1.1E-03
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 None 1.000 1 0 2010 2017
Entrez Id: 959
Gene Symbol: CD40LG
CD40LG
CD40 ligand 0.414 0.846 0.72
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 None 1.000 1 0 2004 2015
Entrez Id: 4773
Gene Symbol: NFATC2
NFATC2
nuclear factor of activated T cells 2 0.525 0.731 1.00
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.500 None 1.000 1 0 2007 2017
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
nitric oxide synthase 2 0.364 0.923 4.0E-15
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.220 None 1.000 1 0 2006 2006
Entrez Id: 3371
Gene Symbol: TNC
TNC
tenascin C 0.433 0.846 1.3E-07
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.210 None 1.000 2 0 2005 2009
Entrez Id: 10911
Gene Symbol: UTS2
UTS2
urotensin 2 0.564 0.808 3.2E-02
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.210 None 1.000 1 0 2004 2005
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.210 None 1.000 1 0 2002 2008
Entrez Id: 183
Gene Symbol: AGT
AGT
angiotensinogen 0.367 0.923 5.0E-08
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.210 None 1.000 1 0 2004 2011
Entrez Id: 284
Gene Symbol: ANGPT1
ANGPT1
angiopoietin 1 0.446 0.808 0.95
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.210 None 1.000 1 0 2006 2008
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
cellular communication network factor 2 0.399 0.846 5.0E-04
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.210 None 1.000 1 0 2005 2009
Entrez Id: 2697
Gene Symbol: GJA1
GJA1
gap junction protein alpha 1 0.393 0.885 0.16
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 2 0 2011 2013
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
platelet derived growth factor subunit B 0.488 0.846 0.77
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 2 0 1993 2011
Entrez Id: 5740
Gene Symbol: PTGIS
PTGIS
prostaglandin I2 synthase 0.617 0.654 1.2E-09
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 2 0 1999 2004
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
heme oxygenase 1 0.381 0.923 9.7E-03
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 2 0 2004 2009
Entrez Id: 522
Gene Symbol: ATP5PF
ATP5PF
ATP synthase peripheral stalk subunit F6 0.716 0.538 6.1E-03
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 2 0 2016 2016
Entrez Id: 857
Gene Symbol: CAV1
CAV1
caveolin 1 0.388 0.885 8.3E-03
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension
phenotype 0.200 None 1.000 2 0 2004 2013