| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
NADH:ubiquinone oxidoreductase subunit S4 | 0.587 | 0.808 | 3.1E-04 |
|
disease | 1.000 | definitive | 0.968 | 12 | 0 | 2001 | 2019 | ||||||||
|
SURF1 cytochrome c oxidase assembly factor | 0.578 | 0.654 | 1.6E-13 |
|
disease | 1.000 | definitive | 0.987 | 9 | 0 | 1998 | 2018 | ||||||||
|
cytochrome c oxidase assembly homolog COX15 | 0.638 | 0.538 | 1.1E-13 |
|
disease | 0.740 | limited | 1.000 | 6 | 0 | 2002 | 2016 | ||||||||
|
succinate dehydrogenase complex flavoprotein subunit A | 0.517 | 0.731 | 2.6E-10 |
|
disease | 0.730 | moderate | 0.917 | 8 | 0 | 1992 | 2017 | ||||||||
|
BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone | 0.534 | 0.808 | 4.7E-13 |
|
disease | 0.700 | limited | 1.000 | 6 | 0 | 1998 | 2017 | ||||||||
|
NADH:ubiquinone oxidoreductase core subunit S3 | 0.581 | 0.769 | 5.8E-04 |
|
disease | 0.640 | moderate | 1.000 | 10 | 0 | 1998 | 2018 | ||||||||
|
NADH:ubiquinone oxidoreductase core subunit S8 | 0.636 | 0.538 | 0.17 |
|
disease | 0.630 | moderate | 1.000 | 9 | 0 | 1998 | 2018 | ||||||||
|
cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 | 0.623 | 0.654 | 8.4E-02 |
|
disease | 0.610 | moderate | 1.000 | 7 | 0 | 1990 | 2015 | ||||||||
|
translational activator of cytochrome c oxidase I | 0.647 | 0.577 | 1.5E-03 |
|
disease | 0.610 | moderate | 1.000 | 3 | 0 | 2009 | 2016 | ||||||||
|
NADH:ubiquinone oxidoreductase core subunit S7 | 0.579 | 0.769 | 0.91 |
|
disease | 0.550 | moderate | 1.000 | 7 | 0 | 1999 | 2019 | ||||||||
|
synthesis of cytochrome C oxidase 2 | 0.479 | 0.846 | 7.5E-07 |
|
disease | 0.540 | definitive | 0.917 | 7 | 0 | 1999 | 2016 | ||||||||
|
NADH:ubiquinone oxidoreductase core subunit S1 | 0.595 | 0.692 | 6.6E-11 |
|
disease | 0.520 | definitive | 1.000 | 12 | 0 | 1991 | 2016 | ||||||||
|
NADH:ubiquinone oxidoreductase subunit A2 | 0.617 | 0.577 | 0.77 |
|
disease | 0.520 | moderate | 1.000 | 9 | 0 | 1998 | 2018 | ||||||||
|
PET100 cytochrome c oxidase chaperone | 0.650 | 0.577 | 3.6E-04 |
|
disease | 0.520 | moderate | 1.000 | 4 | 0 | 1996 | 2015 | ||||||||
|
NADH:ubiquinone oxidoreductase subunit A10 | 0.678 | 0.385 | 6.2E-08 |
|
disease | 0.510 | limited | 1.000 | 5 | 0 | 2011 | 2017 | ||||||||
|
NADH:ubiquinone oxidoreductase subunit A12 | 0.659 | 0.462 | 7.4E-05 |
|
disease | 0.510 | limited | 1.000 | 3 | 0 | 2011 | 2016 | ||||||||
|
NADH:ubiquinone oxidoreductase subunit A9 | 0.653 | 0.385 | 4.8E-03 |
|
disease | 0.500 | moderate | 1.000 | 5 | 0 | 2012 | 2018 | ||||||||
|
isoleucyl-tRNA synthetase 2, mitochondrial | 0.590 | 0.654 | 8.1E-02 |
|
disease | 0.430 | limited | 1.000 | 4 | 0 | 2014 | 2018 | ||||||||
|
FAD dependent oxidoreductase domain containing 1 | 0.633 | 0.462 | 2.0E-16 |
|
disease | 0.420 | moderate | 1.000 | 6 | 0 | 2010 | 2019 | ||||||||
|
leucine rich pentatricopeptide repeat containing | 0.493 | 0.769 | 2.3E-10 |
|
disease | 0.400 | definitive | 1.000 | 8 | 0 | 2001 | 2017 | ||||||||
|
solute carrier family 19 member 3 | 0.610 | 0.692 | 0.10 |
|
disease | 0.340 | definitive | 1.000 | 10 | 0 | 2010 | 2017 | ||||||||
|
NADH:ubiquinone oxidoreductase core subunit V1 | 0.617 | 0.538 | 6.4E-11 |
|
disease | 0.330 | definitive | 1.000 | 10 | 0 | 2001 | 2019 | ||||||||
|
NADH:ubiquinone oxidoreductase subunit A1 | 0.636 | 0.423 | 0.55 |
|
disease | 0.320 | moderate | 1.000 | 10 | 0 | 1996 | 2018 | ||||||||
|
pyruvate dehydrogenase E1 subunit alpha 1 | 0.581 | 0.538 | 0.99 |
|
disease | 0.310 | definitive | 1.000 | 8 | 0 | 1993 | 2017 | ||||||||
|
G elongation factor mitochondrial 1 | 0.623 | 0.692 | 9.3E-13 |
|
disease | 0.310 | moderate | 1.000 | 6 | 0 | 2007 | 2017 |