Source: LHGDN

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.700 None 0.994 52 0 1992 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.700 None 0.990 39 0 2003 2020
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.680 None 1.000 2 0 1988 2016
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
NRAS proto-oncogene, GTPase 0.390 0.808 0.49
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.480 None 1.000 2 0 2003 2017
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
HRas proto-oncogene, GTPase 0.378 0.885 8.0E-02
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.460 None 1.000 2 0 1988 2016
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5
solute carrier family 5 member 5 0.499 0.769 2.9E-03
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.400 None 1.000 7 0 1997 2020
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
peroxisome proliferator activated receptor gamma 0.358 0.885 2.9E-02
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.400 None 1.000 6 0 2001 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.400 None 0.953 5 0 1991 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1
cyclin D1 0.344 0.923 0.89
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.400 None 1.000 5 0 1998 2019
Entrez Id: 7015
Gene Symbol: TERT
TERT
telomerase reverse transcriptase 0.374 0.846 0.99
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.400 None 0.939 4 0 1999 2020
Entrez Id: 7253
Gene Symbol: TSHR
TSHR
thyroid stimulating hormone receptor 0.486 0.808 3.0E-15
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.400 None 0.906 3 0 1991 2018
Entrez Id: 8031
Gene Symbol: NCOA4
NCOA4
nuclear receptor coactivator 4 0.619 0.577 2.2E-06
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.380 None 1.000 1 0 1996 2015
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.360 None 1.000 2 0 2002 2019
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
C-C motif chemokine ligand 2 0.321 0.962 0.61
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.330 None 1.000 1 0 2009 2019
Entrez Id: 5168
Gene Symbol: ENPP2
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2 0.582 0.769 2.8E-03
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.320 None 1.000 2 0 2004 2015
Entrez Id: 2057
Gene Symbol: EPOR
EPOR
erythropoietin receptor 0.526 0.692 1.0E-02
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.310 None 1.000 1 0 2006 2006
Entrez Id: 2056
Gene Symbol: EPO
EPO
erythropoietin 0.381 0.885 1.1E-02
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.310 None 1.000 1 0 2006 2006
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
cyclin dependent kinase inhibitor 1A 0.403 0.769 1.9E-03
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.260 None 1.000 3 0 1996 2014
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.200 None 0.957 3 0 1997 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.200 None 1.000 2 0 2005 2019
Entrez Id: 2778
Gene Symbol: GNAS
GNAS
GNAS complex locus 0.420 0.885 0.68
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.160 None 1.000 1 0 1995 2017
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
galectin 3 0.392 0.846 2.3E-05
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.100 None 1.000 7 0 1997 2020
Entrez Id: 2335
Gene Symbol: FN1
FN1
fibronectin 1 0.365 0.962 1.4E-03
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.100 None 1.000 5 0 1999 2016
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.100 None 1.000 4 0 1995 2019
Entrez Id: 7038
Gene Symbol: TG
TG
thyroglobulin 0.480 0.808 2.9E-59
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.100 None 0.927 4 0 1983 2019