| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
disease | 0.600 | None | 0.867 | 3 | 0 | 1993 | 2019 | ||||||||
|
renin | 0.370 | 0.923 | 2.4E-07 |
|
disease | 0.600 | None | 0.941 | 1 | 0 | 1993 | 2018 | ||||||||
|
natriuretic peptide A | 0.505 | 0.769 | 5.5E-04 |
|
disease | 0.560 | None | 1.000 | 2 | 0 | 1997 | 2014 | ||||||||
|
endothelin 1 | 0.380 | 0.846 | 0.46 |
|
disease | 0.550 | None | 1.000 | 2 | 0 | 1997 | 2016 | ||||||||
|
mechanistic target of rapamycin kinase | 0.343 | 0.885 | 1.00 |
|
disease | 0.520 | None | 1.000 | 1 | 0 | 2004 | 2018 | ||||||||
|
myosin heavy chain 7 | 0.516 | 0.692 | 4.2E-16 |
|
disease | 0.330 | None | 1.000 | 1 | 0 | 1987 | 2016 | ||||||||
|
coenzyme Q7, hydroxylase | 0.736 | 0.462 | 3.8E-06 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 2006 | 2006 | ||||||||
|
angiotensin I converting enzyme 2 | 0.477 | 0.769 | 1.00 |
|
disease | 0.280 | None | 1.000 | 1 | 0 | 2006 | 2019 | ||||||||
|
nitric oxide synthase 3 | 0.378 | 0.885 | 6.7E-07 |
|
disease | 0.270 | None | 1.000 | 1 | 0 | 1997 | 2018 | ||||||||
|
natriuretic peptide B | 0.513 | 0.808 | 9.9E-06 |
|
disease | 0.250 | None | 1.000 | 2 | 0 | 2006 | 2018 | ||||||||
|
adrenoceptor beta 1 | 0.555 | 0.769 | 2.9E-06 |
|
disease | 0.250 | None | 1.000 | 1 | 0 | 2002 | 2010 | ||||||||
|
cellular communication network factor 2 | 0.399 | 0.846 | 5.0E-04 |
|
disease | 0.240 | None | 0.800 | 1 | 0 | 2009 | 2018 | ||||||||
|
cardiotrophin 1 | 0.636 | 0.423 | 4.2E-02 |
|
disease | 0.240 | None | 1.000 | 1 | 0 | 1996 | 2012 | ||||||||
|
sirtuin 1 | 0.378 | 0.885 | 8.7E-02 |
|
disease | 0.220 | None | 1.000 | 2 | 0 | 2008 | 2019 | ||||||||
|
G protein-coupled receptor kinase 2 | 0.532 | 0.654 | 1.00 |
|
disease | 0.220 | None | 1.000 | 1 | 0 | 1999 | 2015 | ||||||||
|
forkhead box O3 | 0.431 | 0.808 | 0.99 |
|
disease | 0.220 | None | 1.000 | 1 | 0 | 2008 | 2019 | ||||||||
|
bradykinin receptor B2 | 0.585 | 0.808 | 0.12 |
|
disease | 0.220 | None | 1.000 | 1 | 0 | 2002 | 2004 | ||||||||
|
natriuretic peptide receptor 1 | 0.608 | 0.654 | 2.9E-04 |
|
disease | 0.210 | None | 1.000 | 1 | 0 | 2006 | 2014 | ||||||||
|
NADPH oxidase 4 | 0.471 | 0.885 | 5.8E-20 |
|
disease | 0.210 | None | 1.000 | 1 | 0 | 2013 | 2019 | ||||||||
|
matrix metallopeptidase 2 | 0.333 | 0.923 | 0.84 |
|
disease | 0.210 | None | 1.000 | 1 | 0 | 2013 | 2017 | ||||||||
|
leptin receptor | 0.433 | 0.808 | 0.99 |
|
disease | 0.210 | None | 1.000 | 1 | 0 | 2008 | 2013 | ||||||||
|
catalase | 0.359 | 0.962 | 1.6E-10 |
|
disease | 0.210 | None | 1.000 | 1 | 0 | 2009 | 2018 | ||||||||
|
protein tyrosine kinase 2 beta | 0.448 | 0.808 | 0.94 |
|
disease | 0.210 | None | 1.000 | 1 | 0 | 2002 | 2007 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
disease | 0.210 | None | 1.000 | 1 | 0 | 2008 | 2019 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.200 | None | 1.000 | 2 | 0 | 2005 | 2012 |