| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
disease | 0.900 | None | 0.947 | 51 | 0 | 1994 | 2020 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
disease | 0.700 | None | 0.965 | 72 | 0 | 1992 | 2020 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.700 | None | 0.963 | 14 | 0 | 1991 | 2020 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
disease | 0.700 | None | 0.951 | 10 | 0 | 1989 | 2019 | ||||||||
|
mutL homolog 1 | 0.399 | 0.808 | 3.4E-05 |
|
disease | 0.700 | None | 0.950 | 4 | 0 | 1994 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.700 | None | 0.984 | 3 | 0 | 1999 | 2019 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.700 | None | 1.000 | 1 | 0 | 1997 | 2019 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.700 | None | 0.903 | 1 | 0 | 1991 | 2019 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
disease | 0.700 | None | 0.966 | 1 | 0 | 2005 | 2020 | ||||||||
|
opioid binding protein/cell adhesion molecule like | 0.606 | 0.654 | 0.23 |
|
disease | 0.630 | None | 1.000 | 2 | 0 | 2003 | 2014 | ||||||||
|
estrogen receptor 1 | 0.324 | 0.962 | 1.00 |
|
disease | 0.600 | None | 0.950 | 1 | 0 | 1995 | 2019 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
disease | 0.500 | None | 0.958 | 3 | 0 | 2002 | 2019 | ||||||||
|
epithelial cell adhesion molecule | 0.451 | 0.885 | 1.3E-07 |
|
disease | 0.490 | None | 0.900 | 1 | 0 | 2004 | 2018 | ||||||||
|
cadherin 1 | 0.401 | 0.808 | 0.15 |
|
disease | 0.480 | None | 1.000 | 2 | 0 | 1994 | 2017 | ||||||||
|
parkin RBR E3 ubiquitin protein ligase | 0.431 | 0.846 | 6.9E-07 |
|
disease | 0.460 | None | 1.000 | 2 | 0 | 2003 | 2019 | ||||||||
|
PMS1 homolog 2, mismatch repair system component | 0.484 | 0.808 | 4.5E-27 |
|
disease | 0.440 | None | 1.000 | 1 | 0 | 2006 | 2019 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
disease | 0.400 | None | 1.000 | 12 | 0 | 1995 | 2019 | ||||||||
|
mucin 16, cell surface associated | 0.479 | 0.808 | 8.3E-112 |
|
disease | 0.400 | None | 1.000 | 5 | 0 | 1987 | 2020 | ||||||||
|
signal transducer and activator of transcription 3 | 0.320 | 0.923 | 1.00 |
|
disease | 0.400 | None | 1.000 | 4 | 0 | 2004 | 2019 | ||||||||
|
mitogen-activated protein kinase 1 | 0.330 | 0.923 | 1.00 |
|
disease | 0.400 | None | 1.000 | 3 | 0 | 2004 | 2019 | ||||||||
|
mechanistic target of rapamycin kinase | 0.343 | 0.885 | 1.00 |
|
disease | 0.400 | None | 1.000 | 2 | 0 | 2004 | 2019 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.400 | None | 0.929 | 2 | 0 | 2003 | 2019 | ||||||||
|
mesothelin | 0.525 | 0.692 | 5.9E-25 |
|
disease | 0.400 | None | 0.957 | 2 | 0 | 2000 | 2020 | ||||||||
|
MYC proto-oncogene, bHLH transcription factor | 0.344 | 0.923 | 1.00 |
|
disease | 0.400 | None | 1.000 | 1 | 0 | 2004 | 2019 | ||||||||
|
tubulin beta 3 class III | 0.486 | 0.808 | 2.6E-10 |
|
disease | 0.390 | None | 1.000 | 3 | 0 | 2005 | 2019 |