Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3777
Gene Symbol: KCNK3
KCNK3
potassium two pore domain channel subfamily K member 3 0.584 0.654 0.90
Idiopathic pulmonary arterial hypertension
disease 0.700 strong 0.952 1 0 2012 2020
Entrez Id: 857
Gene Symbol: CAV1
CAV1
caveolin 1 0.388 0.885 8.3E-03
Idiopathic pulmonary arterial hypertension
disease 0.700 moderate 0.955 1 0 2007 2019
Entrez Id: 659
Gene Symbol: BMPR2
BMPR2
bone morphogenetic protein receptor type 2 0.538 0.654 1.00
Idiopathic pulmonary arterial hypertension
disease 0.700 None 0.978 1 0 2000 2020
Entrez Id: 4093
Gene Symbol: SMAD9
SMAD9
SMAD family member 9 0.666 0.308 6.4E-05
Idiopathic pulmonary arterial hypertension
disease 0.660 None 0.857 1 0 2009 2018
Entrez Id: 94
Gene Symbol: ACVRL1
ACVRL1
activin A receptor like type 1 0.493 0.769 9.7E-04
Idiopathic pulmonary arterial hypertension
disease 0.500 strong 0.971 1 0 2001 2020
Entrez Id: 9496
Gene Symbol: TBX4
TBX4
T-box transcription factor 4 0.576 0.731 0.50
Idiopathic pulmonary arterial hypertension
disease 0.460 strong 1.000 1 0 2013 2020
Entrez Id: 440275
Gene Symbol: EIF2AK4
EIF2AK4
eukaryotic translation initiation factor 2 alpha kinase 4 0.603 0.577 1.2E-15
Idiopathic pulmonary arterial hypertension
disease 0.440 strong 1.000 1 0 2015 2019
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
SMAD family member 4 0.401 0.808 1.00
Idiopathic pulmonary arterial hypertension
disease 0.420 None 1.000 1 0 2008 2018
Entrez Id: 3741
Gene Symbol: KCNA5
KCNA5
potassium voltage-gated channel subfamily A member 5 0.606 0.500 1.1E-03
Idiopathic pulmonary arterial hypertension
disease 0.360 None 0.857 1 0 2007 2019
Entrez Id: 4086
Gene Symbol: SMAD1
SMAD1
SMAD family member 1 0.533 0.731 0.99
Idiopathic pulmonary arterial hypertension
disease 0.350 None 1.000 1 0 2010 2019
Entrez Id: 658
Gene Symbol: BMPR1B
BMPR1B
bone morphogenetic protein receptor type 1B 0.573 0.615 1.00
Idiopathic pulmonary arterial hypertension
disease 0.320 limited 1.000 1 0 2004 2012
Entrez Id: 2034
Gene Symbol: EPAS1
EPAS1
endothelial PAS domain protein 1 0.454 0.731 0.60
Idiopathic pulmonary arterial hypertension
disease 0.320 strong 1.000 1 0 2008 2018
Entrez Id: 7428
Gene Symbol: VHL
VHL
von Hippel-Lindau tumor suppressor 0.443 0.846 8.0E-02
Idiopathic pulmonary arterial hypertension
disease 0.300 strong 1.000 1 0 2011 2011