Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.200 None 0.947 6572 76 1987 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.100 None 0.969 2979 38 1987 2020
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.328 0.923 6.0E-03
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.200 None 0.945 2944 20 1987 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.300 0.885 0.39
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.500 None 0.944 1796 14 1984 2020
Entrez Id: 29126
Gene Symbol: CD274
CD274
CD274 molecule 0.324 0.923 1.9E-02
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.100 None 0.962 1783 0 2003 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.400 None 0.968 1758 12 1992 2020
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.200 None 0.976 1552 15 1997 2020
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.400 None 0.953 1446 13 1983 2020
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.200 None 0.946 1386 14 2002 2020
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.324 0.962 1.00
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.100 None 0.943 1380 16 1981 2020
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
BRCA1 DNA repair associated 0.367 0.923 9.2E-29
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.500 None 0.964 1116 19 1993 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.200 None 0.977 1052 8 1998 2020
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.303 0.885 1.00
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.200 None 0.955 933 10 1994 2020
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2 apoptosis regulator 0.291 0.885 0.56
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.100 None 0.948 886 4 1984 2020
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
hypoxia inducible factor 1 subunit alpha 0.327 0.923 0.98
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.100 None 0.963 725 4 1999 2020
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
H3 histone pseudogene 10 0.350 0.846
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.100 None 0.921 675 0 1994 2020
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta 0.319 0.885 1.00
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.100 None 0.990 669 2 1998 2020
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 0.320 0.885 1.4E-06
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.100 None 0.989 664 1 1998 2020
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta 0.322 0.885 1.00
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.100 None 0.989 662 4 1998 2020
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.320 0.923 1.00
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.100 None 0.984 639 3 1999 2020
Entrez Id: 4609
Gene Symbol: MYC
MYC
MYC proto-oncogene, bHLH transcription factor 0.344 0.923 1.00
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.500 None 0.967 629 1 1983 2020
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.311 0.962 0.98
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.100 None 0.979 611 4 1998 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.100 None 0.978 590 4 1987 2020
Entrez Id: 595
Gene Symbol: CCND1
CCND1
cyclin D1 0.344 0.923 0.89
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.100 None 0.960 577 3 1985 2020
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
mutL homolog 1 0.399 0.808 3.4E-05
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.100 None 0.933 555 17 1993 2020