| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
group | 0.200 | None | 0.947 | 6577 | 76 | 1987 | 2020 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
group | 0.100 | None | 0.969 | 2979 | 38 | 1987 | 2020 | ||||||||
|
APC regulator of WNT signaling pathway | 0.373 | 0.962 | 1.00 |
|
group | 0.200 | None | 0.967 | 424 | 26 | 1991 | 2020 | ||||||||
|
cyclin dependent kinase inhibitor 2A | 0.300 | 0.885 | 0.39 |
|
group | 0.500 | None | 0.944 | 1799 | 21 | 1984 | 2020 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
group | 0.200 | None | 0.945 | 2946 | 20 | 1987 | 2020 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
group | 0.200 | None | 0.946 | 1388 | 20 | 2002 | 2020 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
group | 0.500 | None | 0.964 | 1117 | 19 | 1993 | 2020 | ||||||||
|
mutL homolog 1 | 0.399 | 0.808 | 3.4E-05 |
|
group | 0.100 | None | 0.933 | 555 | 17 | 1993 | 2020 | ||||||||
|
KIT proto-oncogene, receptor tyrosine kinase | 0.366 | 0.808 | 0.98 |
|
group | 0.200 | None | 0.957 | 421 | 17 | 1992 | 2020 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
group | 0.200 | None | 0.976 | 1553 | 16 | 1997 | 2020 | ||||||||
|
estrogen receptor 1 | 0.324 | 0.962 | 1.00 |
|
group | 0.100 | None | 0.943 | 1380 | 16 | 1981 | 2020 | ||||||||
|
ALK receptor tyrosine kinase | 0.396 | 0.846 | 3.2E-06 |
|
group | 0.100 | None | 0.979 | 517 | 15 | 1996 | 2020 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
group | 0.400 | None | 0.953 | 1448 | 13 | 1983 | 2020 | ||||||||
|
mutS homolog 2 | 0.406 | 0.808 | 0.90 |
|
group | 0.100 | None | 0.933 | 313 | 13 | 1993 | 2019 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
group | 0.400 | None | 0.968 | 1758 | 12 | 1992 | 2020 | ||||||||
|
MET proto-oncogene, receptor tyrosine kinase | 0.380 | 0.846 | 0.97 |
|
group | 0.100 | None | 0.949 | 350 | 12 | 1992 | 2020 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
group | 0.200 | None | 0.955 | 934 | 11 | 1994 | 2020 | ||||||||
|
HRas proto-oncogene, GTPase | 0.378 | 0.885 | 8.0E-02 |
|
group | 0.200 | None | 0.975 | 236 | 11 | 1983 | 2019 | ||||||||
|
fibroblast growth factor receptor 2 | 0.380 | 0.808 | 1.00 |
|
group | 0.100 | None | 0.968 | 93 | 11 | 1991 | 2019 | ||||||||
|
phosphoinositide-3-kinase regulatory subunit 1 | 0.477 | 0.885 | 1.00 |
|
group | 0.200 | None | 0.960 | 25 | 11 | 1998 | 2019 | ||||||||
|
ret proto-oncogene | 0.392 | 0.885 | 1.00 |
|
group | 0.200 | None | 0.940 | 336 | 10 | 1989 | 2020 | ||||||||
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
group | 0.100 | None | 0.958 | 431 | 9 | 1995 | 2020 | ||||||||
|
serine/threonine kinase 11 | 0.435 | 0.808 | 0.99 |
|
group | 0.200 | None | 0.976 | 289 | 9 | 1998 | 2020 | ||||||||
|
NRAS proto-oncogene, GTPase | 0.390 | 0.808 | 0.49 |
|
group | 0.200 | None | 0.926 | 189 | 9 | 1986 | 2020 | ||||||||
|
platelet derived growth factor receptor alpha | 0.415 | 0.808 | 1.00 |
|
group | 0.100 | None | 0.950 | 161 | 9 | 1994 | 2019 |