| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.400 | None | 0.966 | 59 | 1 | 1998 | 2020 | ||||||||
|
C-reactive protein | 0.299 | 0.962 | 3.7E-03 |
|
disease | 0.100 | None | 0.942 | 52 | 0 | 2006 | 2020 | ||||||||
|
Pulmonary disease, chronic obstructive, severe early-onset | 0.456 | 0.885 |
|
disease | 0.100 | None | 0.980 | 50 | 0 | 2002 | 2020 | |||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.400 | None | 1.000 | 49 | 1 | 2002 | 2020 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
disease | 0.600 | None | 0.975 | 40 | 0 | 1995 | 2020 | ||||||||
|
interleukin 17A | 0.324 | 0.923 | 4.3E-02 |
|
disease | 0.400 | None | 1.000 | 33 | 0 | 2007 | 2019 | ||||||||
|
interleukin 10 | 0.281 | 0.923 | 5.9E-03 |
|
disease | 0.100 | None | 1.000 | 30 | 0 | 2000 | 2019 | ||||||||
|
C-X-C motif chemokine ligand 8 | 0.310 | 0.962 | 2.7E-04 |
|
disease | 0.100 | None | 1.000 | 29 | 0 | 1996 | 2019 | ||||||||
|
toll like receptor 4 | 0.321 | 0.962 | 4.6E-09 |
|
disease | 0.400 | None | 1.000 | 28 | 2 | 2002 | 2019 | ||||||||
|
NLR family pyrin domain containing 3 | 0.361 | 0.962 | 8.1E-04 |
|
disease | 0.100 | None | 1.000 | 19 | 0 | 2011 | 2020 | ||||||||
|
interleukin 33 | 0.409 | 0.885 | 8.3E-10 |
|
disease | 0.400 | None | 1.000 | 18 | 0 | 2011 | 2020 | ||||||||
|
high mobility group box 1 | 0.368 | 0.923 | 0.82 |
|
disease | 0.100 | None | 0.941 | 17 | 3 | 2012 | 2019 | ||||||||
|
CF transmembrane conductance regulator | 0.424 | 0.885 | 2.2E-58 |
|
disease | 0.200 | None | 0.933 | 15 | 3 | 2004 | 2019 | ||||||||
|
nuclear factor, erythroid 2 like 2 | 0.357 | 0.885 | 3.6E-03 |
|
disease | 0.100 | None | 0.933 | 15 | 0 | 2004 | 2019 | ||||||||
|
interleukin 13 | 0.386 | 0.846 | 1.4E-02 |
|
disease | 0.400 | None | 0.929 | 14 | 0 | 2002 | 2020 | ||||||||
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
disease | 0.100 | None | 0.923 | 13 | 0 | 2002 | 2019 | ||||||||
|
interferon gamma | 0.288 | 0.962 | 0.47 |
|
disease | 0.400 | None | 1.000 | 13 | 0 | 2010 | 2019 | ||||||||
|
mannose binding lectin 2 | 0.390 | 0.846 | 2.7E-03 |
|
disease | 0.100 | None | 1.000 | 13 | 0 | 2004 | 2018 | ||||||||
|
myeloperoxidase | 0.377 | 0.923 | 7.1E-15 |
|
disease | 0.100 | None | 1.000 | 13 | 0 | 2001 | 2019 | ||||||||
|
GA binding protein transcription factor subunit alpha | 0.379 | 0.885 | 1.00 |
|
disease | 0.100 | None | 0.917 | 12 | 0 | 2012 | 2019 | ||||||||
|
MYD88 innate immune signal transduction adaptor | 0.414 | 0.923 | 0.12 |
|
disease | 0.400 | None | 0.917 | 12 | 0 | 2009 | 2020 | ||||||||
|
signal transducer and activator of transcription 3 | 0.320 | 0.923 | 1.00 |
|
disease | 0.100 | None | 1.000 | 12 | 0 | 2006 | 2019 | ||||||||
|
solute carrier family 9 member A6 | 0.516 | 0.846 | 1.00 |
|
disease | 0.100 | None | 1.000 | 10 | 0 | 2009 | 2019 | ||||||||
|
C-X-C motif chemokine ligand 1 | 0.449 | 0.923 | 0.12 |
|
disease | 0.580 | None | 1.000 | 10 | 0 | 1996 | 2019 | ||||||||
|
interleukin 5 | 0.437 | 0.846 | 5.7E-03 |
|
disease | 0.100 | None | 1.000 | 10 | 0 | 2001 | 2019 |