Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 990
Gene Symbol: CDC6
CDC6
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 AlteredExpression LHGDN Expression of Mcm7 and Cdc6 in oral squamous cell carcinoma and precancerous lesions. 19189662

2009

Entrez Id: 2014
Gene Symbol: EMP3
EMP3
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 AlteredExpression LHGDN EMP3 as a tumor suppressor gene for esophageal squamous cell carcinoma. 18823699

2009

Entrez Id: 2175
Gene Symbol: FANCA
FANCA
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 Biomarker LHGDN Fanconi anemia deficiency stimulates HPV-associated hyperplastic growth in organotypic epithelial raft culture. 19015634

2009

Entrez Id: 2634
Gene Symbol: GBP2
GBP2
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 AlteredExpression LHGDN Interferon-inducible guanylate binding protein (GBP)-2: a novel p53-regulated tumor marker in esophageal squamous cell carcinomas. 19003964

2009

Entrez Id: 4327
Gene Symbol: MMP19
MMP19
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 Biomarker LHGDN Matrix metalloproteinase-19 is a predictive marker for tumor invasiveness in patients with oropharyngeal squamous cell carcinoma. 18161657

2008

Entrez Id: 3624
Gene Symbol: INHBA
INHBA
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 AlteredExpression LHGDN Activin a causes cancer cell aggressiveness in esophageal squamous cell carcinoma cells. 17909904

2008

Entrez Id: 4104
Gene Symbol: MAGEA5
MAGEA5
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 Biomarker LHGDN Expression of melanoma-associated antigens in oral squamous cell carcinoma. 18197853

2008

Entrez Id: 252969
Gene Symbol: NEIL2
NEIL2
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 GeneticVariation LHGDN Genotype and haplotypes of the NEIL1 NT_010194.16:g.46434077G>T (rs7182283) and g.46438282C>G (rs4462560) and NEIL2 NT_077531.3:g.4102971C>G (rs804270) polymorphisms were determined for 872 patients with newly diagnosed squamous cell carcinomas of the oral cavity and oropharynx (SCCOOP) and 1,044 cancer-free non-Hispanic white control subjects frequency-matched by age and sex. 18594018

2008

Entrez Id: 1082
Gene Symbol: CGB3
CGB3
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 AlteredExpression LHGDN hCG beta expression by cervical squamous carcinoma--in vivo histological association with tumour invasion and apoptosis. 18752498

2008

Entrez Id: 79661
Gene Symbol: NEIL1
NEIL1
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 GeneticVariation LHGDN Genotype and haplotypes of the NEIL1 NT_010194.16:g.46434077G>T (rs7182283) and g.46438282C>G (rs4462560) and NEIL2 NT_077531.3:g.4102971C>G (rs804270) polymorphisms were determined for 872 patients with newly diagnosed squamous cell carcinomas of the oral cavity and oropharynx (SCCOOP) and 1,044 cancer-free non-Hispanic white control subjects frequency-matched by age and sex. 18594018

2008

Entrez Id: 4105
Gene Symbol: MAGEA6
MAGEA6
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 Biomarker LHGDN Expression of melanoma-associated antigens in oral squamous cell carcinoma. 18197853

2008

Entrez Id: 7153
Gene Symbol: TOP2A
TOP2A
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 AlteredExpression LHGDN Expression of human DNA Topoisomerase II-alpha in squamous cell carcinoma of the larynx and its correlation with clinicopathologic variables. 19019771

2008

Entrez Id: 253738
Gene Symbol: EBF3
EBF3
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 PosttranslationalModification LHGDN Frequently methylated tumor suppressor genes in head and neck squamous cell carcinoma. 18559491

2008

Entrez Id: 64750
Gene Symbol: SMURF2
SMURF2
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 AlteredExpression LHGDN Susceptible genes and molecular pathways related to heavy ion irradiation in oral squamous cell carcinoma cells. 18514338

2008

Entrez Id: 3676
Gene Symbol: ITGA4
ITGA4
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 PosttranslationalModification LHGDN CpG island hypermethylation of E-cadherin (CDH1) and integrin alpha4 is associated with recurrence of early stage esophageal squamous cell carcinoma. 18697202

2008

Entrez Id: 160728
Gene Symbol: SLC5A8
SLC5A8
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 PosttranslationalModification LHGDN Frequently methylated tumor suppressor genes in head and neck squamous cell carcinoma. 18559491

2008

Entrez Id: 7803
Gene Symbol: PTP4A1
PTP4A1
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 AlteredExpression LHGDN Expression of phosphatase of regenerating liver 1 and 3 mRNA in esophageal squamous cell carcinoma. 18684031

2008

Entrez Id: 3756
Gene Symbol: KCNH1
KCNH1
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 AlteredExpression LHGDN Expression and prognostic roles of Eag1 in resected esophageal squamous cell carcinomas. 18080766

2008

Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 Biomarker LHGDN It seems that TNF-alpha-308 G/A may be related to susceptibility, whereas -609 TT TNFR1 and 1690 C/T TNFR2 SNPs may be protective to tobacco-related oral squamous cell carcinoma. 18206417

2008

Entrez Id: 4060
Gene Symbol: LUM
LUM
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 AlteredExpression LHGDN In SqCC and ADC, the expression level of lumican in cancer cells did not correlate with patient prognosis. 19020750

2008

Entrez Id: 3067
Gene Symbol: HDC
HDC
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 AlteredExpression LHGDN Expression of non-mast cell histidine decarboxylase in tumor-associated microvessels in human esophageal squamous cell carcinomas. 19133005

2008

Entrez Id: 79192
Gene Symbol: IRX1
IRX1
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 PosttranslationalModification LHGDN Frequently methylated tumor suppressor genes in head and neck squamous cell carcinoma. 18559491

2008

Entrez Id: 5716
Gene Symbol: PSMD10
PSMD10
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 AlteredExpression LHGDN Gankyrin oncoprotein overexpression as a critical factor for tumor growth in human esophageal squamous cell carcinoma and its clinical significance. 17935131

2008

Entrez Id: 4100
Gene Symbol: MAGEA1
MAGEA1
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 Biomarker LHGDN Expression of melanoma-associated antigens in oral squamous cell carcinoma. 18197853

2008

Entrez Id: 3433
Gene Symbol: IFIT2
IFIT2
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.010 AlteredExpression LHGDN IFN-induced protein with tetratricopeptide repeats 2 inhibits migration activity and increases survival of oral squamous cell carcinoma. 18819931

2008