| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
solute carrier family 6 member 3 | 0.453 | 0.885 | 1.00 |
|
phenotype | 0.100 | None | 0.966 | 29 | 3 | 1998 | 2019 | ||||||||
|
mechanistic target of rapamycin kinase | 0.343 | 0.885 | 1.00 |
|
phenotype | 0.200 | None | 1.000 | 26 | 0 | 2013 | 2020 | ||||||||
|
signal transducer and activator of transcription 3 | 0.320 | 0.923 | 1.00 |
|
phenotype | 0.100 | None | 0.955 | 22 | 0 | 2008 | 2019 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
phenotype | 0.100 | None | 1.000 | 20 | 0 | 1991 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
phenotype | 0.100 | None | 1.000 | 20 | 0 | 2000 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | 0.319 | 0.885 | 1.00 |
|
phenotype | 0.100 | None | 1.000 | 20 | 0 | 2000 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | 0.322 | 0.885 | 1.00 |
|
phenotype | 0.100 | None | 1.000 | 18 | 0 | 2000 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | 0.320 | 0.885 | 1.4E-06 |
|
phenotype | 0.100 | None | 1.000 | 17 | 0 | 2000 | 2019 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
phenotype | 0.100 | None | 1.000 | 16 | 0 | 2006 | 2018 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
phenotype | 0.100 | None | 0.938 | 16 | 0 | 1998 | 2020 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
phenotype | 0.100 | None | 1.000 | 14 | 0 | 2000 | 2020 | ||||||||
|
nuclear receptor subfamily 3 group C member 1 | 0.393 | 0.885 | 0.97 |
|
phenotype | 0.100 | None | 1.000 | 14 | 1 | 2004 | 2019 | ||||||||
|
corticotropin releasing hormone | 0.439 | 0.808 | 0.72 |
|
phenotype | 0.100 | None | 1.000 | 13 | 0 | 2001 | 2018 | ||||||||
|
FMRP translational regulator 1 | 0.473 | 0.769 | 0.65 |
|
phenotype | 0.200 | None | 1.000 | 12 | 0 | 1994 | 2019 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
phenotype | 0.100 | None | 0.917 | 12 | 0 | 2000 | 2020 | ||||||||
|
renin | 0.370 | 0.923 | 2.4E-07 |
|
phenotype | 0.100 | None | 1.000 | 12 | 0 | 2012 | 2019 | ||||||||
|
synaptosome associated protein 25 | 0.489 | 0.808 | 0.99 |
|
phenotype | 0.100 | None | 0.917 | 12 | 2 | 2000 | 2019 | ||||||||
|
NLR family pyrin domain containing 3 | 0.361 | 0.962 | 8.1E-04 |
|
phenotype | 0.100 | None | 1.000 | 11 | 1 | 2013 | 2020 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
phenotype | 0.100 | None | 1.000 | 11 | 0 | 2001 | 2019 | ||||||||
|
brain derived neurotrophic factor | 0.345 | 0.923 | 0.66 |
|
phenotype | 0.100 | None | 1.000 | 11 | 0 | 2005 | 2019 | ||||||||
|
TSC complex subunit 2 | 0.439 | 0.808 | 1.00 |
|
phenotype | 0.100 | None | 0.909 | 11 | 0 | 2010 | 2019 | ||||||||
|
catechol-O-methyltransferase | 0.400 | 0.923 | 1.1E-06 |
|
phenotype | 0.100 | None | 1.000 | 10 | 1 | 2005 | 2016 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
phenotype | 0.100 | None | 1.000 | 10 | 0 | 2006 | 2019 | ||||||||
|
CD40 ligand | 0.414 | 0.846 | 0.72 |
|
phenotype | 0.100 | None | 1.000 | 10 | 0 | 1994 | 2018 | ||||||||
|
coagulation factor IX | 0.465 | 0.885 | 1.00 |
|
phenotype | 0.090 | None | 1.000 | 9 | 0 | 2012 | 2019 |