×
Entrez Id:
6683
Gene Symbol:
SPAST
SPAST
Spastic paraplegia 4, autosomal dominant
1.000
Biomarker
GENOMICS_ENGLAND
×
Entrez Id:
6683
Gene Symbol:
SPAST
SPAST
Spastic paraplegia 4, autosomal dominant
1.000
Biomarker
GENOMICS_ENGLAND
Intragenic modifiers of hereditary spastic paraplegia due to spastin gene mutations.
15248095
2004
×
Entrez Id:
6683
Gene Symbol:
SPAST
SPAST
Spastic paraplegia 4, autosomal dominant
1.000
Biomarker
GENOMICS_ENGLAND
Spastin mutations in sporadic adult-onset upper motor neuron syndromes.
16240363
2005
×
Entrez Id:
6683
Gene Symbol:
SPAST
SPAST
Spastic paraplegia 4, autosomal dominant
1.000
Biomarker
GENOMICS_ENGLAND
The presence of lower motor neuron dysfunction in a subgroup of SPG4 patients suggests that the cellular dysfunction in SPG4 extends beyond the axonal projections of upper motor neurons and ascending sensory pathways.
16832076
2006
×
Entrez Id:
6683
Gene Symbol:
SPAST
SPAST
Spastic paraplegia 4, autosomal dominant
1.000
Biomarker
GENOMICS_ENGLAND
Truncating mutations in SPAST patients are associated with a high rate of psychiatric comorbidities in hereditary spastic paraplegia.
28572275
2017
×
Entrez Id:
6683
Gene Symbol:
SPAST
SPAST
Spastic paraplegia 4, autosomal dominant
1.000
Biomarker
GENOMICS_ENGLAND
Truncating mutations in SPAST patients are associated with a high rate of psychiatric comorbidities in hereditary spastic paraplegia.
28572275
2017
×
Entrez Id:
6683
Gene Symbol:
SPAST
SPAST
Muscle Spasticity
0.460
Biomarker
GENOMICS_ENGLAND
Truncating mutations in SPAST patients are associated with a high rate of psychiatric comorbidities in hereditary spastic paraplegia.
28572275
2017
×
Entrez Id:
6683
Gene Symbol:
SPAST
SPAST
Muscle Spasticity
0.460
Biomarker
GENOMICS_ENGLAND
Truncating mutations in SPAST patients are associated with a high rate of psychiatric comorbidities in hereditary spastic paraplegia.
28572275
2017
×
Entrez Id:
6683
Gene Symbol:
SPAST
SPAST
Inherited neuropathies
0.300
Biomarker
GENOMICS_ENGLAND
Truncating mutations in SPAST patients are associated with a high rate of psychiatric comorbidities in hereditary spastic paraplegia.
28572275
2017
×
Entrez Id:
6683
Gene Symbol:
SPAST
SPAST
Inherited neuropathies
0.300
Biomarker
GENOMICS_ENGLAND
Truncating mutations in SPAST patients are associated with a high rate of psychiatric comorbidities in hereditary spastic paraplegia.
28572275
2017
×
Entrez Id:
6683
Gene Symbol:
SPAST
SPAST
Spasticity, CTCAE
0.300
Biomarker
GENOMICS_ENGLAND
Truncating mutations in SPAST patients are associated with a high rate of psychiatric comorbidities in hereditary spastic paraplegia.
28572275
2017
×
Entrez Id:
6683
Gene Symbol:
SPAST
SPAST
Spasticity, CTCAE
0.300
Biomarker
GENOMICS_ENGLAND
Truncating mutations in SPAST patients are associated with a high rate of psychiatric comorbidities in hereditary spastic paraplegia.
28572275
2017