Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 51024
Gene Symbol: FIS1
FIS1
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Therapeutic RGD Curcumin prevents mitochondrial dynamics disturbances in early 5/6 nephrectomy: Relation to oxidative stress and mitochondrial bioenergetics. 27801955

2017

Entrez Id: 10059
Gene Symbol: DNM1L
DNM1L
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Therapeutic RGD Curcumin prevents mitochondrial dynamics disturbances in early 5/6 nephrectomy: Relation to oxidative stress and mitochondrial bioenergetics. 27801955

2017

Entrez Id: 6469
Gene Symbol: SHH
SHH
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Biomarker RGD Sonic hedgehog is a novel tubule-derived growth factor for interstitial fibroblasts after kidney injury. 24744439

2014

Entrez Id: 3164
Gene Symbol: NR4A1
NR4A1
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 ModifyingMutation RGD Genetic susceptibility and loss of Nr4a1 enhances macrophage-mediated renal injury in CKD. 24722447

2014

Entrez Id: 8694
Gene Symbol: DGAT1
DGAT1
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Biomarker RGD Dysregulation of hepatic fatty acid metabolism in chronic kidney disease. 23045433

2013

Entrez Id: 84649
Gene Symbol: DGAT2
DGAT2
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Biomarker RGD Dysregulation of hepatic fatty acid metabolism in chronic kidney disease. 23045433

2013

Entrez Id: 8678
Gene Symbol: BECN1
BECN1
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Biomarker RGD Mitochondrial impairment in the five-sixth nephrectomy model of chronic renal failure: proteomic approach. 24090408

2013

Entrez Id: 664
Gene Symbol: BNIP3
BNIP3
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Biomarker RGD Mitochondrial impairment in the five-sixth nephrectomy model of chronic renal failure: proteomic approach. 24090408

2013

Entrez Id: 7015
Gene Symbol: TERT
TERT
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Therapeutic RGD Angiogenic effect of endothelial progenitor cells transfected with telomerase reverse transcriptase on peritubular microvessel in five out of six subtotal nephrectomy rats. 23013219

2012

Entrez Id: 3667
Gene Symbol: IRS1
IRS1
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Biomarker RGD Vascular insulin resistance related to endoplasmic reticulum stress in aortas from a rat model of chronic kidney disease. 22942179

2012

Entrez Id: 3643
Gene Symbol: INSR
INSR
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Biomarker RGD Vascular insulin resistance related to endoplasmic reticulum stress in aortas from a rat model of chronic kidney disease. 22942179

2012

Entrez Id: 4023
Gene Symbol: LPL
LPL
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Biomarker RGD Compared to the controls, the CRF group exhibited severe hypertriglyceridemia, significant reduction of the skeletal muscle, myocardium and adipose tissue LPL mRNA and protein abundance. 22009636

2012

Entrez Id: 10631
Gene Symbol: POSTN
POSTN
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Biomarker RGD Periostin: novel tissue and urinary biomarker of progressive renal injury induces a coordinated mesenchymal phenotype in tubular cells. 22167593

2012

Entrez Id: 7498
Gene Symbol: XDH
XDH
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Therapeutic RGD Nicorandil, a K(atp) channel opener, alleviates chronic renal injury by targeting podocytes and macrophages. 22622455

2012

Entrez Id: 2147
Gene Symbol: F2
F2
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Therapeutic RGD 5/6 nephrectomy as a validated rat model mimicking human warfarin-related nephropathy. 22473220

2012

Entrez Id: 1728
Gene Symbol: NQO1
NQO1
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Therapeutic RGD Prevention of salt-induced renal injury by activation of NAD(P)H:quinone oxidoreductase 1, associated with NADPH oxidase. 22227174

2012

Entrez Id: 10560
Gene Symbol: SLC19A2
SLC19A2
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Biomarker RGD Effect of chronic kidney disease on the expression of thiamin and folic acid transporters. 21149507

2011

Entrez Id: 113235
Gene Symbol: SLC46A1
SLC46A1
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Biomarker RGD Effect of chronic kidney disease on the expression of thiamin and folic acid transporters. 21149507

2011

Entrez Id: 6573
Gene Symbol: SLC19A1
SLC19A1
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Biomarker RGD Effect of chronic kidney disease on the expression of thiamin and folic acid transporters. 21149507

2011

Entrez Id: 7412
Gene Symbol: VCAM1
VCAM1
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Biomarker RGD High-calorie diet with moderate protein restriction prevents cachexia and ameliorates oxidative stress, inflammation and proteinuria in experimental chronic kidney disease. 20820841

2010

Entrez Id: 10
Gene Symbol: NAT2
NAT2
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Biomarker RGD This study attempted to determine the effects of CRF on liver P450 isoforms and NAT2 expressions by using a CRF mouse model. 20007296

2010

Entrez Id: 9817
Gene Symbol: KEAP1
KEAP1
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Biomarker RGD Contribution of impaired Nrf2-Keap1 pathway to oxidative stress and inflammation in chronic renal failure. 20007347

2010

Entrez Id: 1644
Gene Symbol: DDC
DDC
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Biomarker RGD Renal dopaminergic system activity in rat remnant kidney up to twenty-six weeks after surgery. 19167406

2009

Entrez Id: 1812
Gene Symbol: DRD1
DRD1
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Therapeutic RGD Delivery of recombinant adeno-associated virus-mediated human tissue kallikrein for therapy of chronic renal failure in rats. 18402547

2008

Entrez Id: 50604
Gene Symbol: IL20
IL20
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Biomarker RGD Interleukin-20 targets renal cells and is associated with chronic kidney disease. 18639518

2008