Source: CURATED
| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
disease | 0.800 | strong | 0.965 | 9 | 15 | 1992 | 2020 | ||||||||
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.450 | 0.885 | 1.00 |
|
disease | 0.510 | None | 1.000 | 4 | 0 | 2014 | 2019 | ||||||||
|
baculoviral IAP repeat containing 5 | 0.495 | 0.731 | 5.6E-02 |
|
disease | 0.330 | None | 1.000 | 4 | 0 | 2005 | 2018 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
disease | 0.700 | None | 0.970 | 4 | 1 | 1989 | 2019 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
disease | 0.700 | limited | 0.974 | 3 | 0 | 2005 | 2020 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.900 | None | 1.000 | 2 | 2 | 1998 | 2019 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
disease | 0.400 | None | 0.982 | 2 | 0 | 1990 | 2019 | ||||||||
|
charged multivesicular body protein 4C | 0.769 | 0.192 | 3.0E-07 |
|
disease | 0.410 | None | 1.000 | 2 | 1 | 2013 | 2019 | ||||||||
|
selenium binding protein 1 | 0.493 | 0.846 | 3.2E-16 |
|
disease | 0.320 | None | 1.000 | 2 | 0 | 2006 | 2008 | ||||||||
|
superoxide dismutase 2 | 0.379 | 0.923 | 0.15 |
|
disease | 0.320 | None | 1.000 | 2 | 0 | 2005 | 2008 | ||||||||
|
mechanistic target of rapamycin kinase | 0.343 | 0.885 | 1.00 |
|
disease | 0.380 | None | 1.000 | 2 | 0 | 2010 | 2019 | ||||||||
|
C-X-C motif chemokine ligand 8 | 0.310 | 0.962 | 2.7E-04 |
|
disease | 0.400 | None | 1.000 | 2 | 0 | 2000 | 2020 | ||||||||
|
RB transcriptional corepressor like 2 | 0.579 | 0.769 | 1.00 |
|
disease | 0.320 | None | 1.000 | 1 | 0 | 2002 | 2013 | ||||||||
|
opioid binding protein/cell adhesion molecule like | 0.606 | 0.654 | 0.23 |
|
disease | 0.610 | None | 1.000 | 1 | 1 | 2003 | 2014 | ||||||||
|
tRNA methyltransferase 11 homolog | 0.729 | 0.269 | 3.9E-12 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
BCL9 transcription coactivator | 0.595 | 0.615 | 0.50 |
|
disease | 0.320 | None | 1.000 | 1 | 0 | 2011 | 2019 | ||||||||
|
S-phase kinase associated protein 2 | 0.492 | 0.808 | 0.96 |
|
disease | 0.340 | None | 1.000 | 1 | 0 | 2009 | 2019 | ||||||||
|
solute carrier family 2 member 1 | 0.388 | 0.808 | 0.99 |
|
disease | 0.320 | None | 1.000 | 1 | 0 | 2004 | 2018 | ||||||||
|
solute carrier family 5 member 5 | 0.499 | 0.769 | 2.9E-03 |
|
disease | 0.330 | None | 0.750 | 1 | 0 | 2003 | 2018 | ||||||||
|
pleckstrin homology and FYVE domain containing 1 | 0.743 | 0.385 | 1.3E-02 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 2011 | 2011 | ||||||||
|
superoxide dismutase 1 | 0.379 | 0.962 | 0.18 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2005 | 2010 | ||||||||
|
secreted protein acidic and cysteine rich | 0.445 | 0.846 | 0.89 |
|
disease | 0.380 | None | 1.000 | 1 | 0 | 1999 | 2019 | ||||||||
|
RAD51 paralog D | 0.674 | 0.385 | 1.1E-09 |
|
disease | 0.600 | strong | 0.824 | 1 | 0 | 2011 | 2019 | ||||||||
|
RAD51 paralog C | 0.533 | 0.692 | 6.2E-14 |
|
disease | 0.700 | strong | 0.947 | 1 | 0 | 2010 | 2020 | ||||||||
|
desumoylating isopeptidase 2 | 0.691 | 0.385 | 0.85 |
|
disease | 0.320 | None | 1.000 | 1 | 0 | 2009 | 2011 |