×
Entrez Id:
657
Gene Symbol:
BMPR1A
BMPR1A
JUVENILE POLYPOSIS OF STOMACH
0.800
Biomarker
CLINGEN
Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes.
11536076
2001
×
Entrez Id:
657
Gene Symbol:
BMPR1A
BMPR1A
JUVENILE POLYPOSIS OF STOMACH
0.800
Biomarker
CLINGEN
BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling.
15378062
2004
×
Entrez Id:
657
Gene Symbol:
BMPR1A
BMPR1A
JUVENILE POLYPOSIS OF STOMACH
0.800
Biomarker
CLINGEN
Cyclooxygenase-2 expression in polyps from a patient with juvenile polyposis syndrome with mutant BMPR1A.
17325551
2007
×
Entrez Id:
657
Gene Symbol:
BMPR1A
BMPR1A
JUVENILE POLYPOSIS OF STOMACH
0.800
Biomarker
CLINGEN
Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis.
11381269
2001
×
Entrez Id:
2022
Gene Symbol:
ENG
ENG
JUVENILE POLYPOSIS OF STOMACH
0.500
Biomarker
CLINGEN
Syndecan-1, Epithelial-Mesenchymal Transition Markers (E-cadherin/β-catenin) and Neoangiogenesis-related Proteins (PCAM-1 and Endoglin) in Colorectal Cancer.
27127133
2016
×
Entrez Id:
2022
Gene Symbol:
ENG
ENG
JUVENILE POLYPOSIS OF STOMACH
0.500
Biomarker
CLINGEN
Prevalence of germline PTEN, BMPR1A, SMAD4, STK11, and ENG mutations in patients with moderate-load colorectal polyps.
23399955
2013
×
Entrez Id:
2022
Gene Symbol:
ENG
ENG
JUVENILE POLYPOSIS OF STOMACH
0.500
Biomarker
CLINGEN
Molecular classification of patients with unexplained hamartomatous and hyperplastic polyposis.
16287957
2005
×
Entrez Id:
4089
Gene Symbol:
SMAD4
SMAD4
JUVENILE POLYPOSIS OF STOMACH
0.800
Biomarker
CLINGEN
Targeted deletion of Smad4 shows it is required for transforming growth factor beta and activin signaling in colorectal cancer cells.
9482899
1998
×
Entrez Id:
4089
Gene Symbol:
SMAD4
SMAD4
JUVENILE POLYPOSIS OF STOMACH
0.800
Biomarker
CLINGEN
A gene for familial juvenile polyposis maps to chromosome 18q21.1.
9545410
1998
×
Entrez Id:
4089
Gene Symbol:
SMAD4
SMAD4
JUVENILE POLYPOSIS OF STOMACH
0.800
Biomarker
CLINGEN
Smad-dependent and Smad-independent pathways in TGF-beta family signalling.
14534577
2003
×
Entrez Id:
4089
Gene Symbol:
SMAD4
SMAD4
JUVENILE POLYPOSIS OF STOMACH
0.800
Biomarker
CLINGEN
The prevalence of MADH4 and BMPR1A mutations in juvenile polyposis and absence of BMPR2, BMPR1B, and ACVR1 mutations.
15235019
2004
×
Entrez Id:
4089
Gene Symbol:
SMAD4
SMAD4
JUVENILE POLYPOSIS OF STOMACH
0.800
Biomarker
CLINGEN
Smad4 acts as tumor suppressor by antagonizing lymphangiogenesis in colorectal cancer.
25680269
2015
×
Entrez Id:
4089
Gene Symbol:
SMAD4
SMAD4
JUVENILE POLYPOSIS OF STOMACH
0.800
Biomarker
CLINGEN
Mutations in the SMAD4/DPC4 gene in juvenile polyposis.
9582123
1998
×
Entrez Id:
4089
Gene Symbol:
SMAD4
SMAD4
JUVENILE POLYPOSIS OF STOMACH
0.800
Biomarker
CLINGEN
Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes.
9506519
1998