×
Entrez Id: 156
Gene Symbol: GRK2
GRK2
Heart failure
0.600
Therapeutic
RGD
(-)-Epigallocatechin-3-gallate, the major green tea catechin, regulates the desensitization of β1 adrenoceptor via GRK2 in experimental heart failure .
29247373 2018
×
Entrez Id: 4317
Gene Symbol: MMP8
MMP8
Heart failure
0.200
ModifyingMutation
RGD
MMP-8 and MMP-14 protein levels increased later during heart failure progression.10773235 2000
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Heart failure
0.600
Therapeutic
RGD
Tumor necrosis factor-alpha (TNF-alpha ) probably affects the pathogenesis of heart failure .11668085 2001
×
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
Heart failure
0.300
Biomarker
RGD
Activation of signaling molecules and matrix metalloproteinases in right ventricular myocardium of rats with pulmonary hypertension.
17913382 2007
×
Entrez Id: 408
Gene Symbol: ARRB1
ARRB1
Heart failure
0.210
Therapeutic
RGD
Adrenal-targeted, adenoviral-mediated gene delivery in vivo in 2-week post-MI rats, a time point around which circulating aldosterone significantly increases to accelerate HF progression, was performed to either increase the expression of adrenal βarr1 or inhibit its function via expression of a βarr1 C-terminal-derived peptide fragment.
21232674 2011
×
Entrez Id: 4191
Gene Symbol: MDH2
MDH2
Heart failure
0.200
Biomarker
RGD
Adriamycin induced myocardial failure in rats: protective role of Centella asiatica.
16786185 2007
×
Entrez Id: 8678
Gene Symbol: BECN1
BECN1
Heart failure
0.200
Therapeutic
RGD
Adriamycin-induced autophagic cardiomyocyte death plays a pathogenic role in a rat model of heart failure.
18619688 2009
×
Entrez Id: 3586
Gene Symbol: IL10
IL10
Heart failure
0.280
Therapeutic
RGD
Aerobic exercise improves the inflammatory profile correlated with cardiac remodeling and function in chronic heart failure rats.
23778495 2013
×
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
Heart failure
0.500
Biomarker
RGD
Alterations in G protein and MAP kinase signaling pathways during cardiac remodeling in hypertension and heart failure.
12642504 2003
×
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
Heart failure
0.230
Biomarker
RGD
Angiotensin II-mediated posttranslational modification of nNOS in the PVN of rats with CHF: role for PIN.
23832698 2013
×
Entrez Id: 8655
Gene Symbol: DYNLL1
DYNLL1
Heart failure
0.210
Biomarker
RGD
Angiotensin II-mediated posttranslational modification of nNOS in the PVN of rats with CHF: role for PIN.
23832698 2013
×
Entrez Id: 1636
Gene Symbol: ACE
ACE
Heart failure
0.600
Biomarker
RGD
Angiotensin-converting enzyme inhibition promotes coronary angiogenesis in the failing heart of Dahl salt-sensitive hypertensive rats.
22123369 2011
×
Entrez Id: 6546
Gene Symbol: SLC8A1
SLC8A1
Heart failure
0.290
Biomarker
RGD
Angiotensin-converting enzyme inhibitor improves force and Ca2 +--frequency relationships in myocytes from rats with heart failure.
17536604 2007
×
Entrez Id: 4624
Gene Symbol: MYH6
MYH6
Heart failure
0.250
Therapeutic
RGD
Antiplatelet therapy attenuates subcellular remodelling in congestive heart failure.
18088389 2009
×
Entrez Id: 4625
Gene Symbol: MYH7
MYH7
Heart failure
0.250
Therapeutic
RGD
Antiplatelet therapy attenuates subcellular remodelling in congestive heart failure.
18088389 2009
×
Entrez Id: 2022
Gene Symbol: ENG
ENG
Heart failure
0.220
Biomarker
RGD
Atorvastatin decreased left ventricular TGF-beta1, endoglin , and collagen I protein expression and fibrotic area in a rat model of volume overload heart failure .
20156938 2010
×
Entrez Id: 2022
Gene Symbol: ENG
ENG
Heart failure
0.220
Therapeutic
RGD
Atorvastatin decreased left ventricular TGF-beta1, endoglin , and collagen I protein expression and fibrotic area in a rat model of volume overload heart failure .
20156938 2010
×
Entrez Id: 5578
Gene Symbol: PRKCA
PRKCA
Heart failure
0.290
Biomarker
RGD
Augmented protein kinase C-alpha-induced myofilament protein phosphorylation contributes to myofilament dysfunction in experimental congestive heart failure.
17556659 2007
×
Entrez Id: 7054
Gene Symbol: TH
TH
Heart failure
0.220
Biomarker
RGD
Bilateral PVN infusions of NBI-27914 attenuated the decreases in PVN GABA and GAD67, and the increases in RSNA, ACTH and PVN glutamate, NE and TH observed in HF rats.
21287352 2011
×
Entrez Id: 4852
Gene Symbol: NPY
NPY
Heart failure
0.230
Biomarker
RGD
Cardiac and renal tissue NPY decreased with heart failure , proportionate to the severity of renal complications.
17804485 2007
×
Entrez Id: 2353
Gene Symbol: FOS
FOS
Heart failure
0.200
Biomarker
RGD
Cardiac gene expression profile in rats with terminal heart failure and cachexia.
15623567 2005
×
Entrez Id: 8061
Gene Symbol: FOSL1
FOSL1
Heart failure
0.200
Biomarker
RGD
Cardiac gene expression profile in rats with terminal heart failure and cachexia.
15623567 2005
×
Entrez Id: 8473
Gene Symbol: OGT
OGT
Heart failure
0.200
Biomarker
RGD
Cardiac O-GlcNAc signaling is increased in hypertrophy and heart failure.
22128088 2012
×
Entrez Id: 845
Gene Symbol: CASQ2
CASQ2
Heart failure
0.250
Biomarker
RGD
Changes in ion channel gene expression underlying heart failure-induced sinoatrial node dysfunction.
21565973 2011
×
Entrez Id: 6334
Gene Symbol: SCN8A
SCN8A
Heart failure
0.200
Biomarker
RGD
Correspondingly, the relative mRNA levels of the neuronal isoforms SCN1a and SCN8a increased 2.5- and 2.7-fold, respectively; SCN3a did not change, whereas SCN5a decreased by approximately 60% in HF .
19584134 2009