Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
Squamous cell carcinoma of the head and neck
disease 0.500 None 0.973 219 86 1991 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
Squamous cell carcinoma of the head and neck
disease 0.500 None 1.000 68 29 2001 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
Squamous cell carcinoma of the head and neck
disease 0.500 None 0.982 277 18 1992 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.300 0.885 0.39
Squamous cell carcinoma of the head and neck
disease 0.500 None 0.983 115 9 1994 2019
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
F-box and WD repeat domain containing 7 0.465 0.808 1.00
Squamous cell carcinoma of the head and neck
disease 0.120 None 1.000 3 7 2016 2019
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
HRas proto-oncogene, GTPase 0.378 0.885 8.0E-02
Squamous cell carcinoma of the head and neck
disease 0.150 None 1.000 6 6 1990 2018
Entrez Id: 1870
Gene Symbol: E2F2
E2F2
E2F transcription factor 2 0.599 0.692 0.26
Squamous cell carcinoma of the head and neck
disease 0.010 None 1.000 1 6 2012 2012
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
ERCC excision repair 2, TFIIH core complex helicase subunit 0.420 0.846 7.1E-20
Squamous cell carcinoma of the head and neck
disease 0.080 None 0.875 8 5 2000 2017
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
nuclear factor, erythroid 2 like 2 0.357 0.885 3.6E-03
Squamous cell carcinoma of the head and neck
disease 0.440 None 1.000 5 5 2013 2019
Entrez Id: 4548
Gene Symbol: MTR
MTR
5-methyltetrahydrofolate-homocysteine methyltransferase 0.482 0.808 2.4E-12
Squamous cell carcinoma of the head and neck
disease 0.040 None 1.000 4 4 2005 2012
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
Squamous cell carcinoma of the head and neck
disease 0.130 None 0.750 4 4 2003 2016
Entrez Id: 11332
Gene Symbol: ACOT7
ACOT7
acyl-CoA thioesterase 7 0.531 0.769 0.76
Squamous cell carcinoma of the head and neck
disease 0.010 None 1.000 1 4 1998 1998
Entrez Id: 7127
Gene Symbol: TNFAIP2
TNFAIP2
TNF alpha induced protein 2 0.711 0.423 8.3E-05
Squamous cell carcinoma of the head and neck
disease 0.010 None 1.000 1 4 2011 2011
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
Squamous cell carcinoma of the head and neck
disease 0.400 None 0.966 29 3 1999 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
Squamous cell carcinoma of the head and neck
disease 0.800 strong 0.952 21 3 1972 2019
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
X-ray repair cross complementing 1 0.421 0.923 6.3E-09
Squamous cell carcinoma of the head and neck
disease 0.100 None 0.905 21 3 1992 2020
Entrez Id: 7517
Gene Symbol: XRCC3
XRCC3
X-ray repair cross complementing 3 0.505 0.769 1.9E-10
Squamous cell carcinoma of the head and neck
disease 0.090 None 0.889 9 3 2002 2016
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
methylenetetrahydrofolate reductase 0.337 0.885 3.2E-10
Squamous cell carcinoma of the head and neck
disease 0.060 None 1.000 6 3 2005 2012
Entrez Id: 1869
Gene Symbol: E2F1
E2F1
E2F transcription factor 1 0.441 0.846 0.99
Squamous cell carcinoma of the head and neck
disease 0.050 None 1.000 5 3 1998 2012
Entrez Id: 2072
Gene Symbol: ERCC4
ERCC4
ERCC excision repair 4, endonuclease catalytic subunit 0.468 0.846 1.4E-12
Squamous cell carcinoma of the head and neck
disease 0.050 None 1.000 5 3 2011 2019
Entrez Id: 3621
Gene Symbol: ING1
ING1
inhibitor of growth family member 1 0.573 0.692 9.7E-03
Squamous cell carcinoma of the head and neck
disease 0.710 None 1.000 2 3 2000 2000
Entrez Id: 4552
Gene Symbol: MTRR
MTRR
5-methyltetrahydrofolate-homocysteine methyltransferase reductase 0.502 0.808 2.2E-14
Squamous cell carcinoma of the head and neck
disease 0.020 None 1.000 2 3 2005 2007
Entrez Id: 7421
Gene Symbol: VDR
VDR
vitamin D receptor 0.352 0.885 1.7E-05
Squamous cell carcinoma of the head and neck
disease 0.020 None 1.000 2 3 2005 2011
Entrez Id: 3815
Gene Symbol: KIT
KIT
KIT proto-oncogene, receptor tyrosine kinase 0.366 0.808 0.98
Squamous cell carcinoma of the head and neck
disease 0.010 None 1.000 1 3 2017 2017
Entrez Id: 567
Gene Symbol: B2M
B2M
beta-2-microglobulin 0.447 0.846 0.56
Squamous cell carcinoma of the head and neck
disease 0.100 None 1.000 1 3 2016 2016