| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
protein tyrosine phosphatase non-receptor type 22 | 0.438 | 0.846 | 3.5E-21 |
|
group | 0.500 | None | 0.948 | 213 | 4 | 2004 | 2019 | ||||||||
|
interleukin 17A | 0.324 | 0.923 | 4.3E-02 |
|
group | 0.400 | None | 0.976 | 209 | 1 | 2005 | 2020 | ||||||||
|
cytotoxic T-lymphocyte associated protein 4 | 0.369 | 0.923 | 0.94 |
|
group | 0.100 | None | 0.941 | 204 | 3 | 1996 | 2019 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
group | 0.100 | None | 0.963 | 187 | 1 | 1987 | 2020 | ||||||||
|
forkhead box P3 | 0.368 | 0.846 | 0.99 |
|
group | 0.100 | None | 0.968 | 156 | 1 | 2002 | 2020 | ||||||||
|
autoimmune regulator | 0.516 | 0.808 | 4.0E-12 |
|
group | 0.100 | None | 0.980 | 101 | 5 | 1993 | 2019 | ||||||||
|
interleukin 10 | 0.281 | 0.923 | 5.9E-03 |
|
group | 0.100 | None | 0.979 | 94 | 0 | 1996 | 2020 | ||||||||
|
interleukin 2 | 0.336 | 0.885 | 0.48 |
|
group | 0.100 | None | 0.989 | 88 | 0 | 1989 | 2020 | ||||||||
|
major histocompatibility complex, class II, DR beta 1 | 0.333 | 0.923 | 1.1E-03 |
|
group | 0.100 | None | 0.963 | 82 | 0 | 1992 | 2019 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
group | 0.400 | None | 0.987 | 76 | 1 | 1989 | 2020 | ||||||||
|
interleukin 2 receptor subunit alpha | 0.389 | 0.885 | 5.5E-02 |
|
group | 0.200 | None | 0.960 | 75 | 2 | 2002 | 2020 | ||||||||
|
TNF superfamily member 13b | 0.460 | 0.731 | 0.98 |
|
group | 0.100 | None | 0.971 | 70 | 1 | 1999 | 2020 | ||||||||
|
interferon gamma | 0.288 | 0.962 | 0.47 |
|
group | 0.400 | None | 1.000 | 64 | 0 | 1987 | 2019 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
group | 0.100 | None | 1.000 | 61 | 0 | 1993 | 2020 | ||||||||
|
interferon stimulated exonuclease gene 20 | 0.414 | 0.846 | 2.9E-03 |
|
group | 0.100 | None | 0.963 | 54 | 0 | 2002 | 2020 | ||||||||
|
interleukin 23 subunit alpha | 0.415 | 0.846 | 0.36 |
|
group | 0.100 | None | 1.000 | 51 | 0 | 2005 | 2019 | ||||||||
|
insulin | 0.445 | 0.923 | 0.30 |
|
group | 0.100 | None | 0.940 | 50 | 1 | 1980 | 2019 | ||||||||
|
interferon alpha 1 | 0.371 | 0.923 |
|
group | 0.100 | None | 0.958 | 48 | 0 | 1999 | 2020 | |||||||||
|
interferon alpha 13 | 0.374 | 0.923 |
|
group | 0.100 | None | 0.958 | 48 | 0 | 1999 | 2020 | |||||||||
|
vitamin D receptor | 0.352 | 0.885 | 1.7E-05 |
|
group | 0.100 | None | 0.957 | 47 | 3 | 2000 | 2019 | ||||||||
|
CD40 molecule | 0.396 | 0.846 | 0.85 |
|
group | 0.200 | None | 1.000 | 47 | 2 | 1996 | 2020 | ||||||||
|
T cell receptor beta variable 20/OR9-2 (non-functional) | 0.403 | 0.923 |
|
group | 0.100 | None | 1.000 | 46 | 0 | 1990 | 2019 | |||||||||
|
signal transducer and activator of transcription 4 | 0.471 | 0.769 | 0.77 |
|
group | 0.200 | None | 0.956 | 45 | 3 | 2008 | 2019 | ||||||||
|
interferon regulatory factor 5 | 0.489 | 0.731 | 9.0E-03 |
|
group | 0.200 | None | 0.953 | 43 | 3 | 2006 | 2020 | ||||||||
|
interleukin 21 | 0.441 | 0.769 | 0.63 |
|
group | 0.100 | None | 1.000 | 40 | 2 | 2004 | 2020 |