| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
betaine--homocysteine S-methyltransferase 2 | 0.792 | 0.231 | 2.0E-15 |
|
disease | 0.010 | None | < 0.001 | 1 | 1 | 2005 | 2005 | ||||||||
|
FKBP prolyl isomerase 8 | 0.839 | 0.231 | 1.00 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2008 | 2008 | ||||||||
|
ankyrin repeat and EF-hand domain containing 1 | 0.890 | 0.231 | 8.5E-10 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
tripartite motif containing 36 | 0.780 | 0.231 | 3.4E-05 |
|
disease | 0.100 | None | 0 | 0 | |||||||||||
|
NK2 homeobox 8 | 0.769 | 0.269 | 4.9E-03 |
|
disease | 0.010 | None | 1.000 | 1 | 2 | 2013 | 2013 | ||||||||
|
tRNA aspartic acid methyltransferase 1 | 0.743 | 0.308 | 3.6E-10 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2009 | 2009 | ||||||||
|
inositol-tetrakisphosphate 1-kinase | 0.760 | 0.346 | 0.99 |
|
disease | 0.010 | None | 1.000 | 1 | 1 | 2014 | 2014 | ||||||||
|
scribble planar cell polarity protein | 0.691 | 0.423 | 0.93 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2013 | 2018 | ||||||||
|
protein-L-isoaspartate (D-aspartate) O-methyltransferase | 0.691 | 0.423 | 0.78 |
|
disease | 0.320 | None | 1.000 | 2 | 2 | 2006 | 2012 | ||||||||
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.666 | 0.423 | 2.4E-03 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2009 | 2009 | ||||||||
|
solute carrier family 5 member 11 | 0.792 | 0.423 | 1.7E-13 |
|
disease | 0.010 | None | 1.000 | 1 | 3 | 2004 | 2004 | ||||||||
|
prickle planar cell polarity protein 2 | 0.711 | 0.423 | 1.00 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2010 | 2010 | ||||||||
|
dishevelled segment polarity protein 1 pseudogene 1 | 0.716 | 0.423 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 | |||||||||
|
G protein-coupled receptor 161 | 0.686 | 0.462 | 3.5E-04 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
homeobox C cluster | 0.695 | 0.462 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2002 | 2002 | |||||||||
|
cadherin EGF LAG seven-pass G-type receptor 1 | 0.700 | 0.500 | 1.00 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2014 | 2018 | ||||||||
|
growth differentiation factor 6 | 0.587 | 0.500 | 0.99 |
|
disease | 0.100 | None | 0 | 0 | |||||||||||
|
growth differentiation factor 3 | 0.595 | 0.500 | 4.1E-05 |
|
disease | 0.100 | None | 0 | 0 | |||||||||||
|
3-hydroxyanthranilate 3,4-dioxygenase | 0.644 | 0.538 | 1.1E-08 |
|
disease | 0.100 | None | 1.000 | 1 | 1 | 2017 | 2017 | ||||||||
|
homeobox B cluster | 0.631 | 0.538 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2002 | 2002 | |||||||||
|
homeobox D cluster | 0.631 | 0.538 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2002 | 2002 | |||||||||
|
VANGL planar cell polarity protein 1 | 0.570 | 0.538 | 2.0E-02 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2009 | 2009 | ||||||||
|
cytochrome P450 family 26 subfamily A member 1 | 0.619 | 0.577 | 8.4E-11 |
|
disease | 0.020 | None | 0.500 | 2 | 0 | 2006 | 2006 | ||||||||
|
SUZ12 polycomb repressive complex 2 subunit | 0.529 | 0.577 | 1.00 |
|
disease | 0.200 | None | 1.000 | 1 | 0 | 2010 | 2010 | ||||||||
|
jumonji and AT-rich interaction domain containing 2 | 0.615 | 0.577 | 1.00 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2004 | 2004 |