| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
major histocompatibility complex, class II, DR beta 1 | 0.333 | 0.923 | 1.1E-03 |
|
disease | 0.500 | None | 0.923 | 323 | 5 | 1992 | 2020 | ||||||||
|
interferon beta 1 | 0.421 | 0.846 |
|
disease | 0.400 | None | 0.958 | 308 | 0 | 1995 | 2020 | |||||||||
|
myelin basic protein | 0.510 | 0.885 | 0.28 |
|
disease | 0.100 | None | 0.939 | 163 | 0 | 1990 | 2020 | ||||||||
|
RNA binding motif protein 45 | 0.383 | 0.846 | 2.1E-10 |
|
disease | 0.100 | None | 0.922 | 153 | 2 | 1992 | 2020 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.300 | None | 0.880 | 133 | 1 | 1990 | 2020 | ||||||||
|
myelin oligodendrocyte glycoprotein | 0.546 | 0.731 | 0.14 |
|
disease | 0.100 | None | 0.972 | 109 | 3 | 1995 | 2020 | ||||||||
|
multiple sclerosis | 0.599 | 0.692 |
|
disease | 0.100 | None | 0.981 | 105 | 0 | 1998 | 2020 | |||||||||
|
interleukin 17A | 0.324 | 0.923 | 4.3E-02 |
|
disease | 0.400 | None | 0.986 | 74 | 1 | 1999 | 2020 | ||||||||
|
interleukin 2 receptor subunit alpha | 0.389 | 0.885 | 5.5E-02 |
|
disease | 0.500 | None | 0.985 | 68 | 11 | 1994 | 2019 | ||||||||
|
interferon gamma | 0.288 | 0.962 | 0.47 |
|
disease | 0.400 | None | 0.970 | 67 | 1 | 1994 | 2020 | ||||||||
|
aquaporin 4 | 0.456 | 0.885 | 2.3E-03 |
|
disease | 0.100 | None | 0.970 | 66 | 0 | 2006 | 2020 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.400 | None | 0.877 | 65 | 2 | 1994 | 2019 | ||||||||
|
interleukin 10 | 0.281 | 0.923 | 5.9E-03 |
|
disease | 0.400 | None | 0.922 | 64 | 3 | 1996 | 2019 | ||||||||
|
vitamin D receptor | 0.352 | 0.885 | 1.7E-05 |
|
disease | 0.400 | None | 0.891 | 64 | 5 | 1999 | 2019 | ||||||||
|
interleukin 7 receptor | 0.487 | 0.769 | 3.8E-07 |
|
disease | 0.500 | None | 0.982 | 55 | 7 | 2003 | 2019 | ||||||||
|
colony stimulating factor 2 | 0.330 | 0.962 | 0.83 |
|
disease | 0.100 | None | 0.981 | 54 | 0 | 1996 | 2020 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.100 | None | 0.957 | 47 | 1 | 1996 | 2019 | ||||||||
|
cytotoxic T-lymphocyte associated protein 4 | 0.369 | 0.923 | 0.94 |
|
disease | 0.100 | None | 0.860 | 43 | 5 | 1998 | 2020 | ||||||||
|
major histocompatibility complex, class II, DQ alpha 1 | 0.416 | 0.846 | 2.4E-02 |
|
disease | 0.200 | None | 0.884 | 43 | 3 | 1991 | 2019 | ||||||||
|
laminin subunit gamma 2 | 0.389 | 0.923 | 2.9E-12 |
|
disease | 0.100 | None | 1.000 | 43 | 0 | 2017 | 2020 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
disease | 0.400 | None | 0.905 | 42 | 2 | 1997 | 2019 | ||||||||
|
matrix metallopeptidase 9 | 0.305 | 0.923 | 1.9E-17 |
|
disease | 0.100 | None | 0.927 | 41 | 1 | 1996 | 2019 | ||||||||
|
brain derived neurotrophic factor | 0.345 | 0.923 | 0.66 |
|
disease | 0.100 | None | 0.975 | 40 | 3 | 1999 | 2019 | ||||||||
|
keratin 20 | 0.388 | 0.846 | 9.1E-11 |
|
disease | 0.100 | None | 1.000 | 38 | 0 | 2010 | 2020 | ||||||||
|
membrane spanning 4-domains A1 | 0.411 | 0.846 | 5.1E-05 |
|
disease | 0.100 | None | 1.000 | 38 | 0 | 2010 | 2020 |